Wide-field Ophthalmic Space-Division Multiplexing Optical Coherence Tomography.
Wide-field Ophthalmic Space-Division Multiplexing Optical Coherence Tomography.
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DOI：
10.1364/prj.383034
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发表时间：
2020-04
影响因子：
7.6
通讯作者：
Zhou C
中科院分区：
文献类型：
--
作者：
Jerwick J;Huang Y;Dong Z;Slaudades A;Brucker AJ;Zhou C
高速眼科光学相干断层扫描系统备受关注，因为它们可以实现快速、无运动和宽视场的视网膜成像。空分复用光学相干断层扫描 (SDM-OCT) 是一种高速成像技术，利用微机电垂直腔表面发射激光器 (MEM VCSEL) 源的长相干长度，沿单个成像深度复用多个图像。我们展示了宽视场视网膜 OCT 成像，以 800,000 A 扫描/秒的有效 A 扫描速率获取，并在不到 1 秒的时间内获取视网膜上覆盖高达 12.5 mm × 7.4 mm 的体积图像。进行了一项临床可行性研究，将眼科 SDM-OCT 与商业 OCT 系统进行比较，说明 SDM-OCT 在临床环境中的高速能力。
High-speed ophthalmic optical coherence tomography systems are of interest because they allow rapid, motion-free, and wide-field retinal imaging. Space-division multiplexing optical coherence tomography (SDM-OCT) is a high-speed imaging technology which takes advantage of the long coherence length of microelectromechanical vertical cavity surface emitting laser (MEMs VCSEL) sources to multiplex multiple images along a single imaging depth. We demonstrate wide-field retinal OCT imaging, acquired at an effective A-scan rate of 800,000 A-scans/sec with volumetric images covering up to 12.5 mm × 7.4 mm on the retina acquired in less than 1 second. A clinical feasibility study was conducted to compare the ophthalmic SDM-OCT with commercial OCT systems, illustrating the high-speed capability of SDM-OCT in a clinical setting.