Costly major histocompatibility complex signals produced only by reproductively active males, but not females, must be validated by a 'maleness signal' in three-spined sticklebacks
Costly major histocompatibility complex signals produced only by reproductively active males, but not females, must be validated by a 'maleness signal' in three-spined sticklebacks
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DOI：
10.1098/rspb.2009.1501
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发表时间：
2010-02-07
影响因子：
4.7
通讯作者：
Boehm, Thomas
中科院分区：
文献类型：
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作者：
Milinski, Manfred;Griffiths, Sian W.;Boehm, Thomas
有关个体主要组织相容性复合体 (MHC) 免疫基因型的嗅觉信息对于多个物种的配偶选择非常重要。例如，在三刺鱼的择偶决策中，雌性会根据传递有关其 MHC 多样性信息的气味线索来评估雄性。在这里，我们表明需要额外的“男性”信号来验证 MHC 信号。此外，利用刺鱼的天然气味和合成的 MHC 配体肽之间的相互作用，我们表明 MHC 信号取决于雄性的生殖状态。相比之下，我们发现怀孕的雌性不会产生这样的信号。由于与择偶决策相关的 MHC 嗅觉信号取决于性别和生殖状态，因此我们认为，它们的制造对于发送者来说可能成本高昂，因此可能取决于发送者的健康/寄生状态。我们假设肽-MHC 复合物的脱落会损害免疫功能，从而选择不无条件使用这些信号。
Olfactory information about individual major histocompatibility complex (MHC) immune genotypes is important for mate choice in several species. For example, during the mate choice decisions of three-spined sticklebacks, females assess males on the basis of odour cues that convey information about their MHC diversity. Here, we show that an additional 'maleness' signal is needed to validate the MHC signal. Furthermore, using interaction between natural odour of sticklebacks and synthetic MHC-ligand peptides, we show that MHC signals are conditional on the reproductive state in males. By contrast, we find that gravid females do not produce such signals. Since MHC olfactory signals relevant to mate choice decisions are conditional upon gender and reproductive state, we suggest that their manufacture is likely to be costly to senders, and therefore, potentially conditional on the health/parasitization status of the sender. We hypothesize that shedding of peptide-MHC complexes compromises immune function, selecting against unconditional use of these signals.