Measurement of cell mechanical properties by cell compression microdevice
Measurement of cell mechanical properties by cell compression microdevice
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通过细胞压缩微型装置测量细胞机械性能
DOI：
10.1109/mhs.2015.7438339
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
and Yoshitaka Nakanishi
中科院分区：
文献类型：
--
作者：
Tairo Yokokura;Yuta Nakashima;Yukihiro Yonemoto;Yuki Hikichi;and Yoshitaka Nakanishi
本文提出了一种利用微加工器件测量细胞杨氏模量的方法。该方法基于两个过程。第一步是使用制造的微器件进行细胞压缩实验。第二步是理论计算，与实验结果进行比较。设计了一种用于控制细胞压力大小的微型细胞压缩装置。该装置由微通道、细胞培养室和培养室上用于向细胞施加压力的隔膜组成。细胞从细胞培养室上方的隔膜直接压缩。在细胞压缩实验中测量细胞应变量与所施加的压力的关系。根据实验结果，确定了电池的杨氏模量。对细胞的杨氏模量测量所获得的结果与其他研究人员先前测量的值比较相似。
This paper presents a measurement method for Young's modulus of cells using fabricated microdevice. This presented method is based on two processes. A first step is cell compressive experiment using fabricated microdevice. The second step is a theoretical calculation for comparing with the experimental results. Cell compression microdevice was designed for controlling the magnitude of pressure to cells. The device consists of microchannels, cell culture chambers, and a diaphragm on the culture chamber for applying pressure to cells. The cells are directly compressed from the diaphragm above the cell culture chamber. The cell strain amount to the applied pressure was measured in the cell compressive experiment. Based on the experimental results, the Young's modulus of cell was determined. The results obtained on Young's modulus measurement of cells are comparatively similar to previously measured values by other researchers.
DOI：
10.1136/ebmh.11.4.102
发表时间：
2008-10
期刊：
Evidence Based Mental Health
影响因子：
--
作者：
P. Cochat;L. Vaucoret;J. Sarles
通讯作者：
P. Cochat;L. Vaucoret;J. Sarles
使用原子力显微镜表征成骨细胞的动态细胞粘附
影响因子：
3.7
作者：
A. Simon;T. Cohen;M. Porte;J. Aimé;J. Amédée;R. Bareille;C. Baquey
通讯作者：
C. Baquey
影响因子：
20.3
作者：
Glenister, FK;Coppel, RL;Cooke, BM
通讯作者：
Cooke, BM