Eight-Fold Intensification of Electrochemical Azidooxygenation with a Flow-Through Electrode
Eight-Fold Intensification of Electrochemical Azidooxygenation with a Flow-Through Electrode
复制标题
DOI：
10.1021/acssuschemeng.2c01525
复制
发表时间：
2022-06-13
影响因子：
8.4
通讯作者：
Wiley, Benjamin J.
中科院分区：
文献类型：
--
作者：
Guo, Shichen;Kim, Myung Jun;Wiley, Benjamin J.
找到减少反应器体积同时增加有机电反应产物产量的方法将有助于在商业环境中更广泛地采用这种反应来生产化学品。这项工作研究了不同电极结构的流动的使用如何影响生产率（即，产物生成速率）。流动和间歇工艺与碳纸（CP）的比较表明，流动反应器的生产率提高了3.8倍。在流动反应器中研究了三种定制的碳电极，烧结碳纸（S-CP），碳纤维（CNF）和复合碳微纤维（MNC），以评估电极结构的变化如何影响生产率。在最佳条件下，这些电极的生产率分别比普通间歇式反应器高5.4、6.5和7.8倍。将带有MNC电极的流动反应器的出口再循环回到入口，在36分钟内获得81%的产率，而间歇式反应器在5小时内获得75%的产率。这些发现表明，通过使用新型流通电极，可以大大提高电有机反应的生产率。
Finding ways to reduce reactor volume while increasing product output for electro-organic reactions would facilitate the broader adoption of such reactions for the production of chemicals in a commercial setting. This work investigates how the use of flow with different electrode structures impacts the productivity (i.e., the rate of product generation) of a TEMPO-mediated azidooxygenation reaction. Comparison of a flow and batch process with carbon paper (CP) demonstrated a 3.8-fold-higher productivity for the flow reactor. Three custom carbon electrodes, sintered carbon paper (S-CP), carbon nanofiber (CNF), and composite carbon microfiber-nanofiber (MNC), were studied in the flow reactor to evaluate how changing the electrode structure affected productivity. Under the optimum conditions, these electrodes achieved productivities 5.4, 6.5, and 7.8 times higher than the average batch reactor, respectively. Recycling the outlet from the flow reactor with the MNC electrode back into the inlet achieved an 81% yield in 36 min, while the batch reactor obtained a 75% yield in 5 h. These findings demonstrate that the productivity of electro-organic reactions can be substantially improved through the use of novel flow-through electrodes.