Characterization of Malassezia microbiota in the human external auditory canal and on the sole of the foot
Characterization of Malassezia microbiota in the human external auditory canal and on the sole of the foot
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DOI：
10.1111/j.1348-0421.2012.00430.x
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发表时间：
2012-04-01
影响因子：
2.6
通讯作者：
Sugita, Takashi
中科院分区：
文献类型：
--
作者：
Zhang, Enshi;Tanaka, Takafumi;Sugita, Takashi
在真菌皮肤微生物群中，亲脂性酵母属马拉色菌在所有身体部位占优势。在该属的成员中，M. globosa，M. restricta和M.合轴肌最常见于面部、四肢和躯干。在本研究中，马拉色菌微生物在外耳道和脚底的特点。M.在外耳道和足底的寄生虫种类中，以斯氏蚤最多见，其次是M.限制。主成分分析进一步揭示了外耳道和脚底上的马拉色菌菌群与头皮和脸颊上以及鼻腔中的马拉色菌菌群构成不同的聚类。此外，在足底和外耳道检测到5种新的马拉色菌型。我们的研究结果表明，一个独特的马拉色菌微生物群存在于外耳道和脚底，虽然这一发现的临床意义仍然未知。
Of the fungal skin microbiota, the lipophilic yeast genus Malassezia predominates at all body sites. Of the members of this genus, M. globosa, M. restricta, and M. sympodialis are the most common on the face, limbs, and trunk. In the present study, the Malassezia microbiotas in the external auditory canal and on the sole of the foot were characterized. M. slooffiae was the most common species in both the external auditory canal and on the sole of the foot, followed by M. restricta. Principal component analysis further revealed that the Malassezia microbiota in the external auditory canal and on the sole of the foot constitute a different cluster from those on the scalp and cheek and in the nasal cavity. Additionally, five new Malassezia phylotypes were detected on the sole of the foot and in the external auditory canal. Our results suggest that a distinctive Malassezia microbiota is present in the external auditory canal and on the sole of the foot, although the clinical significance of this finding remains unknown.