Vagus nerve stimulation for epilepsy: A review of the peripheral mechanisms.
Vagus nerve stimulation for epilepsy: A review of the peripheral mechanisms.
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DOI：
10.4103/2152-7806.91610
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发表时间：
2012-01-01
影响因子：
--
通讯作者：
Krahl, Scott E
中科院分区：
文献类型：
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作者：
Krahl, Scott E
迷走神经刺激（VNS）是一种独特的癫痫治疗方法，通过外周干预来治疗与大脑内发生的病理事件完全相关的疾病。为了了解如何使用刺激迷走神经来阻止癫痫发作，了解迷走神经的周围解剖结构和生理学至关重要。本综述讨论了迷走神经的外周方面，解释了哪些纤维和分支参与产生这些抗癫痫作用，并推测了改善治疗的潜力。
Vagus nerve stimulation (VNS) is a unique epilepsy treatment in that a peripheral intervention is used to treat a disease that is entirely related to pathological events occurring within the brain. To understand how stimulation of the vagus nerve can be used to stop seizures, an understanding of the peripheral anatomy and physiology of the vagus nerve is essential. The peripheral aspects of the vagus nerve are discussed in this review, with an explanation of which fibers and branches are involved in producing these antiepileptic effects, along with speculation about the potential for improving the therapy.