A MOLECULAR MAP OF THE HUMAN MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-III REGION LINKING COMPLEMENT GENES-C4, GENE-C2 AND FACTOR-B
A MOLECULAR MAP OF THE HUMAN MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-III REGION LINKING COMPLEMENT GENES-C4, GENE-C2 AND FACTOR-B
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DOI：
10.1038/307237a0
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发表时间：
1984-01-01
期刊：
影响因子：
64.8
通讯作者：
PORTER, RR
中科院分区：
文献类型：
--
作者：
CARROLL, MC;CAMPBELL, RD;PORTER, RR
4个人类补体基因，以前被定位在6号染色体上的HLA-D和HLA-B之间，现在已经在基因组DNA的4个重叠粘粒克隆的基础上在染色体的98-kb（kb）区段上进行了比对。C2 [补体成分2]和因子B基因，相隔< 2 kb，是30 kb的2个C4基因，彼此通过约10 kb。
Four human complement genes, which were previously mapped between HLA-D and HLA-B on chromosome 6, have now been aligned on a 98-kilobase (kb) section of the chromosome of the basis of 4 overlapping cosmid clones of genomic DNA. The C2 [complement component 2] and factor B genes, < 2 kb apart, are .apprx. 30 kb from 2 C4 genes separated from each other by .apprx. 10 kb.