Improved prognosis for infants of very low birthweight.
Improved prognosis for infants of very low birthweight.
复制标题
改善极低出生体重婴儿的预后。
DOI：
10.1097/00006254-197507000-00013
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发表时间：
1974
期刊：
影响因子：
8
通讯作者：
E. Reynolds
中科院分区：
文献类型：
--
作者：
A. Stewart;E. Reynolds
在推出针对极低出生体重儿的重症监护方案后，自1966年至1970年的五年间，共有197名出生时体重在1,500克或以下的婴儿在伦敦大学学院医院的新生儿科接受护理。在此期间，体重为501至1,000克的婴儿的新生儿存活率为23%，体重为1,001至1,500克的婴儿的新生儿存活率为69%。死亡的主要直接原因是出生时的缺氧或肺透明膜病。98例存活儿童中95例获得随访，年龄2岁10个月~7岁10个月，平均5岁2个月。他们都进行了反复的体检和发育评估。65名年龄较大的孩子也接受了智商测试。结果显示，86名(90.5%)儿童无明显残疾，4名(4.2%)仅有肢体残疾，S(5.3%)有智力残疾，包括两名肢体残疾儿童。在被推定为严重缺氧的婴儿中，残疾的发生率比其余婴儿要高得多。我们得出结论，重症监护既可以增加极低出生体重儿的存活机会，又可以减少幸存者严重残疾的发生率。
Following the introduction of a program of intensive care for infants of very low birthweight, 197 infants who weighed 1,500 gm or less at birth were cared for in the Neonatal Unit of University College Hospital, London, in the five years from 1966 to 1970. During this period, the neonatal survival rate for infants weighing 501 to 1,000 gm was 23% and for those weighing 1,001 to 1,500 gm was 69%. The principal immediate cause of death was hypoxia around the time of birth or hyaline membrane disease. Ninety-five of the 98 surviving children, aged 2 years 10 months to 7 years 10 months (mean, 5 years 2 months) were followed up. They all had repeated physical examinations and developmental assessments. Sixty-five of the older children also had IQ tests. The results showed that 86 (90.5%) of the children had no detectable handicap, 4 (4.2%) had physical handicaps only, and S (5.3%) had mental handicaps, including two children with physical handicaps. The incidence of handicap was very much greater among infants presumed to have been severely hypoxic than among the remaining infants. We conclude that intensive care can both increase the chance of survival for infants of very low birthweight amid reduce the incidence of serious handicap in survivors.