Effects of alpha-casozepine (Zylkene) versus selegiline hydrochloride (Selgian, Anipryl) on anxiety disorders in dogs
Effects of alpha-casozepine (Zylkene) versus selegiline hydrochloride (Selgian, Anipryl) on anxiety disorders in dogs
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DOI：
10.1016/j.jveb.2007.08.001
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发表时间：
2007-09-01
影响因子：
1.8
通讯作者：
Lefranc, Catherine
中科院分区：
文献类型：
--
作者：
Beata, Claude;Beaumont-Graff, Edith;Lefranc, Catherine
在第一项研究显示对猫的焦虑症有效之后，研究了α-酪氮平（胰蛋白酶牛α-酪蛋白水解产物）对狗的焦虑症的推定作用。该试验是针对对照分子司来吉兰进行的。由经认证的行为主义外科医生在兽医实践中招募了38只犬。针对参比分子司来吉兰的56天试验表明，两种产品均有效降低EDED评分，并且在其成功评分之间未发现统计学差异。主人的评估在统计学上也完全等同。由于这种疗效及其安全性，α-卡索平（Zylkene）应被兽医视为除强制性行为改变外的焦虑生物学管理的一种选择。(C)2007年爱思唯尔公司All rights reserved.
After a first Study Showing efficacy on anxiety disorders in cats, the Putative effects of alpha-casozepine (a tryptic bovine alpha sl-casein hydrolysate) on anxious disorders in dogs was investigated. The trial was conducted against a control molecule, selegiline. Thirty-eight dogs were recruited within veterinary practices by certified behaviorist Surgeons. This 56 day trial, against the reference molecule, selegiline, showed that both Products were efficient to decrease the EDED score and no Statistical difference was found between their success score. Owners assessment was also statistically perfectly equivalent. Due to this efficacy, and to its safety, alpha-casozepine (Zylkene) should be considered an option by the veterinary Surgeon for the biological management of anxiety beside the compulsory behavior modifications. (C) 2007 Elsevier Inc. All rights reserved.