Reference values of clinical chemistry and hematology parameters in rhesus monkeys (Macaca mulatta)
Reference values of clinical chemistry and hematology parameters in rhesus monkeys (Macaca mulatta)
复制标题
恒河猴（Macaca Mulatta）临床化学和血液学参数参考值
DOI：
10.1111/j.1399-3089.2009.00554.x
复制
发表时间：
2009-11-01
影响因子：
3.9
通讯作者：
Cheng, Jingqiu
中科院分区：
文献类型：
--
作者：
Chen, Younan;Qin, Shengfang;Cheng, Jingqiu
背景：恒河猴模型对人类生物学的研究具有重要意义。需要恒河猴临床化学和血液学参数的参考值，以便正确解释数据。方法：采集3 ~ 5岁健康雌雄恒河猴36只全血。检测常规化学和血液学参数，以及一些特殊凝血参数，包括血栓弹性图和凝血因子活性。结果与结论：我们给出了正常中国恒河猴临床化学和血液学参数的基线值。这些数据可能为兽医和研究人员在实验研究中使用恒河猴提供有价值的信息。
Background:Rhesus monkey models are valuable to the studies of human biology. Reference values for clinical chemistry and hematology parameters of rhesus monkeys are required for proper data interpretation.Methods:Whole blood was collected from 36 healthy Chinese rhesus monkeys (Macaca mulatta) of either sex, 3 to 5 yr old. Routine chemistry and hematology parameters, and some special coagulation parameters including thromboelastograph and activities of coagulation factors were tested.Results and conclusion:We presented here the baseline values of clinical chemistry and hematology parameters in normal Chinese rhesus monkeys. These data may provide valuable information for veterinarians and investigators using rhesus monkeys in experimental studies.