Morbidity, mortality, and technical factors of distal pancreatectomy

Morbidity, mortality, and technical factors of distal pancreatectomy
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DOI:
10.1016/s0002-9610(02)00790-0
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发表时间:
2002-03-01
影响因子:
3
通讯作者:
Bold, RJ
Bold, RJ
中科院分区:
医学3区
文献类型:
--
作者:
Fahy, BN;Frey, CF;Bold, RJ

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背景:胰腺渗漏是胰腺手术相关疾病的主要来源。我们试图确定与远端胰腺切除术后发病率和死亡率相关的疾病和技术依赖因素。方法:回顾性分析5年来行远端胰腺切除术的患者。临床、技术和病理数据与手术发病率或死亡率相关。结果:51例患者因原发性胰腺疾病、胰腺外恶性肿瘤或创伤行远端胰腺切除术。围手术期总死亡率和发病率分别为4%和47%。胰漏是最常见的并发症,发生率为26%。创伤后远端胰腺切除术和胰残端缝合闭合患者的总体并发症和胰漏发生率更高。结论:胰腺远端切除术死亡率低,但胰漏是常见的发病原因。手术的紧迫性和胰残端闭合的方法可能影响术后发病率。(C) 2002年医药股份有限公司版权所有。
Background: Pancreatic leak is a major source of morbidity associated with pancreatic surgery. We sought to identify disease and technique-dependent factors associated with morbidity and mortality after distal pancreatectomy.Methods: Retrospective review of patients who underwent distal pancreatectomy during a 5-year period. Clinical, technical, and pathologic data were correlated with operative morbidity or mortality.Results: Fifty-one patients underwent distal pancreatectomy for primary pancreatic disease, extrapancreatic malignancy, or trauma. Overall perioperative mortality and morbidity rates were 4% and 47%, respectively. Pancreatic leak was the most common complication, occurring in 26% of patients. Overall complications and pancreatic leaks occurred more often after distal pancreatectomy for trauma and in patients with a sutured pancreatic stump closure.Conclusions: Distal pancreatectomy can be performed with a low rate of mortality, though pancreatic leak is a common cause of morbidity. The urgency of the procedure and the method of pancreatic stump closure may influence postoperative morbidity. (C) 2002 Excerpta Medica, Inc. All rights reserved.