Increased symptoms in female IBS patients with dysmenorrhea and PMS
Increased symptoms in female IBS patients with dysmenorrhea and PMS
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DOI：
10.1097/00001610-200601000-00002
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发表时间：
2006-01-01
影响因子：
0.8
通讯作者：
Heitkemper, Margaret
中科院分区：
文献类型：
--
作者：
Altman, Gaylene;Cain, Kevin C.;Heitkemper, Margaret
患有肠易激综合症的女性经常会出现经前不适综合症和痛经。采用描述性四组比较设计来比较患有肠易激综合征（18-45 岁）的女性（伴或不伴痛经和经前期困扰综合征）的症状和心理困扰水平。合并 1995 年至 2004 年间收集的三项针对肠易激综合征女性 (n = 226) 的数据。其中，38 名患者自我报告患有肠易激综合征并伴有痛经和经前不适综合征，59 名患者患有肠易激综合征并伴有经前不适综合征，15 名患者患有肠易激综合征和痛经，其余 114 名患者仅患有肠易激综合征。参与者完成了症状检查表 90 修订版和症状日记。比较黄体期、月经期以及从黄体期到月经期的变化期间的疼痛症状和焦虑、抑郁、愤怒和认知困难的计算量表。经前不适综合征和痛经对月经期子宫痉挛有很大影响，而对黄体期和月经期的其他疼痛症状影响较弱。经前痛苦综合症与黄体期和月经期的抑郁、愤怒和认知问题的增加有关。然而，除了子宫痉挛之外，它与从黄体期到月经期的任何症状的增加无关。患有肠易激综合症和经前不适综合症的女性报告的多种症状表明，这一群体的治疗可能特别具有挑战性，可能需要采取多方面的（例如教育、饮食、放松、认知重建）方法。
Women with irritable bowel syndrome often report premenstrual distress syndrome and dysmenorrhea. A descriptive, four-group comparison design was used to compare the symptoms and psychological distress levels of women with irritable bowel syndrome (age 18-45 years) with and without dysmenorrhea and premenstrual distress syndrome. Data from three studies on women with irritable bowel syndrome (n = 226) collected between 1995 and 2004 were combined. Of these, 38 had self-reported irritable bowel syndrome with dysmenorrhea and premenstrual distress syndrome, 59 had irritable bowel syndrome with premenstrual distress syndrome, 15 had irritable bowel syndrome and dysmenorrhea, and the remaining 114 had irritable bowel syndrome only.Participants completed the Symptom Checklist-90 Revised and a symptom diary. Pain symptoms and computed scales of anxiety, depression, anger, and cognitive difficulties were compared during the luteal phase, menses phase, and for the change from luteal to menses phases. Premenstrual distress syndrome and dysmenorrhea had a strong impact on uterine cramping at menses, and a weaker effect on other pain symptoms at both luteal and menses phases. Premenstrual distress syndrome was associated with higher depression, anger, and cognitive problems at both luteal and menses phases; however, it was not associated with a greater increase from luteal to menses phases for any symptoms other than uterine cramping. The multiple symptoms reported by women with both irritable bowel syndrome and premenstrual distress syndrome suggest that this group may be particularly challenging to treat and may require a multicomponent (e.g., education, diet, relaxation, cognitive restructuring) approach.