Transition-Metal-Catalyzed Carboxylation Reactions with Carbon Dioxide.
Transition-Metal-Catalyzed Carboxylation Reactions with Carbon Dioxide.
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DOI：
10.1002/anie.201803186
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发表时间：
2018-12
影响因子：
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通讯作者：
A. Tortajada;Francisco Juliá-Hernández;Marino Börjesson;Toni Moragas;R. Martín
中科院分区：
文献类型：
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作者：
A. Tortajada;Francisco Juliá-Hernández;Marino Börjesson;Toni Moragas;R. Martín
由于CO2作为一种丰富、廉价和可再生的C1化学原料的固有合成潜力，近年来，人们对设计催化CO2固定到有机物中重新产生了兴趣。虽然通过催化CO2固定形成C-C键在很长一段时间内仍然相当有限，但仔细研究最近的文献数据表明，催化羧化反应已经进入了指数增长的新时代，发展成为一个成熟的学科，可以简化羧酸的合成，在工业上具有最大的相关性。这些策略已被普遍证明具有广泛的适用性和便于执行。然而，仍然需要解决重大挑战，以概念性和简洁的方式强调涵盖金属催化羧化领域的必要性，描绘在这个充满活力的专业领域中慢慢出现的潜在新原则。
Driven by the inherent synthetic potential of CO2 as an abundant, inexpensive and renewable C1 chemical feedstock, the recent years have witnessed renewed interest in devising catalytic CO2 fixations into organic matter. Although the formation of C-C bonds via catalytic CO2 fixation remained rather limited for a long period of time, a close look into the recent literature data indicates that catalytic carboxylation reactions have entered a new era of exponential growth, evolving into a mature discipline that allows for streamlining the synthesis of carboxylic acids, building blocks of utmost relevance in industrial endeavors. These strategies have generally proven broadly applicability and convenient to perform. However, substantial challenges still need to be addressed reinforcing the need to cover metal-catalyzed carboxylation area in a conceptual and concise manner, delineating the underlying new principles that are slowly emerging in this vibrant area of expertise.