Gender differences in colorectal polyps and tumors
Gender differences in colorectal polyps and tumors
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DOI：
10.1111/j.1572-0241.2001.03638.x
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发表时间：
2001-03-01
影响因子：
9.8
通讯作者：
de Garmo, P
中科院分区：
文献类型：
--
作者：
McCashland, TM;Brand, R;de Garmo, P
目的：使用国家内窥镜检查数据库（科里），以确定1）是否注意到在息肉和肿瘤的患病率和位置的性别差异; 2）女性是否有更高的率右侧息肉或肿瘤;和3）年龄是否影响这些result.METHODS：科里数据库从1997年4月1日至1999年2月19日，在计算机生成的报告中捕获，进行了分析。本研究的息肉定义为无蒂或有蒂且>9 mm。肿瘤定义为腺癌特征性病变（肿块，苹果核）。纯右侧结肠（PRS）定义为盲肠，升，肝曲;右侧为PRS加上横结肠;左侧为脾曲，降，乙状结肠和直肠。结果：男性比女性有更大的风险息肉[比值比（OR），1.5]和肿瘤（OR，1.4）。结肠镜检查发现息肉和肿瘤的风险随着年龄的增长而增加，相对于60岁的患者，>69岁的患者风险最高。女性患纯右侧息肉（OR，1.2）、肿瘤（OR，1.6）和右侧肿瘤（OR，1.5）的风险高于男性。结论：男性结肠息肉和肿瘤的患病率高于女性。随着年龄的增长，息肉或肿瘤形成的风险逐渐增加。女性有更多的纯右侧息肉和肿瘤发展。需要结肠镜检查来正确诊断老年人右侧病变的发病率增加。(C)2001年，我Cell.胃肠病学
OBJECTIVES: To use a national endoscopy database (CORI) to determine 1) whether gender differences are noted in the prevalence and location of polyps and tumors; 2) whether women have a higher rate of right-sided polyps or tumors; and 3) whether age influences these results.METHODS: CORI database from April 1, 1997 to February 19, 1999, captured in a computer-generated report, was analyzed. Polyps for this study were defined as sessile or pedunculated and as >9 mm. Tumors were defined as lesions characteristic of adenocarcinoma (mass, apple-core). Pure right-sided colon (PRS) was defined as cecum, ascending, hepatic flexure; right-sided as PRS plus the transverse colon; and left-sided as the splenic flexure, descending, sigmoid and rectum.RESULTS: Men have a greater risk of polyps [odds ratio (OR), 1.5] and tumors (OR, 1.4) than women. The risk of finding polyps and tumors at colonoscopy increases with age, with the highest risk noted in those >69 yr of age relative to patients 60 yr of age. Women have a greater risk of developing pure right-sided polyps (OR, 1.2), tumors (OR, 1.6) and right-sided tumors (OR, 1.5) than men.CONCLUSIONS: Men have a higher prevalence of colon polyps and tumors than women. A progressive risk of polyp or tumor formation is noted with aging. Women had a greater number of pure right-sided polyps and tumor development. Colonoscopy is needed to correctly diagnose an increasing prevalence of right-sided pathology in the elderly. (C) 2001 by Am. Cell. of Gastroenterology.