Age and smoking-adjusted lung cancer incidence in a Utah county with a steel mill.

Age and smoking-adjusted lung cancer incidence in a Utah county with a steel mill.
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犹他州一个拥有钢铁厂的县的肺癌发病率随年龄和吸烟的变化而变化。

DOI:
10.1080/00039896.1993.9940819
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发表时间:
1993
期刊:
Archives of environmental health
影响因子:
--
通讯作者:
Lyon,JL
Lyon,JL
中科院分区:
--
文献类型:
--
作者:
Blindauer,KM;Erickson,L;Mcelwee,N;Sorenson,G;Gren,LH;Lyon,JL

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在最近的一项城市空气污染研究中,将犹他州有钢厂的县与没有钢厂的县进行了比较。结果发现,38% 的呼吸道癌死亡可归因于工厂排放的空气污染。之前的研究中的吸烟率没有进行调整,但假设两个县的吸烟率相似。我们使用从正在进行的氡和肺癌病例对照研究中获得的吸烟信息来调整吸烟情况,结果发现,与其他城市县和农村县相比,有钢厂的县的男性、女性不吸烟者和男性吸烟者的呼吸道癌发病率没有差异。与其他城市县相比,有钢厂县的女性吸烟者肺癌发病率略高(比率[RR] = 1.3,95%置信区间[95% CI] = 1.0-1.6),但对不吸烟女性没有影响。我们的结论是,先前研究的结果可以用钢厂所在县与其他县之间吸烟率的差异来解释。
In a recent study of urban air pollution, a Utah county with a steel mill was compared with a county without a steel mill. The result was that 38% of respiratory cancer deaths could be attributed to the air pollution emanating from the mill. Rates for smoking in this previous study were not adjusted, but assumed rates were similar in both counties. We used smoking information obtained from an ongoing radon and lung cancer case-control study to adjust for smoking, and no difference was found in incidence rates of respiratory cancer in the county with the steel mill, compared with the other urban counties and the rural counties among male and female nonsmokers and male smokers. There was a slight excess of lung cancer among female smokers in the county with the steel mill when compared with the other urban counties (rate ratio [RR] = 1.3, 95% confidence interval [95% CI] = 1.0–1.6), but there was no effect in nonsmoking women. We conclude that the findings of the previous study can be explained by differences in smoking rates between the county with the steel mill and the other counties.