Visceral pain

Visceral pain
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DOI:
10.1016/s0140-6736(99)01306-9
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发表时间:
1999-06-19
期刊:
影响因子:
168.9
通讯作者:
Laird, JMA
Laird, JMA
中科院分区:
医学1区
文献类型:
--
作者:
Cervero, F;Laird, JMA

文献摘要

被引文献

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内脏疼痛是由疾病产生的最常见的疼痛形式,也是患者寻求医疗照顾的最常见原因之一。然而,我们对疼痛机制的了解,大部分来自于对躯体而非内脏伤害感受的实验研究。传统观点认为内脏痛只是躯体痛的一种变体,这种观点基于一种单一的神经机制负责所有疼痛的信念。然而,我们对躯体和内脏疼痛的机制了解得越多,我们就越意识到,尽管这两个过程有很多共同点,但它们也有重要的差异。虽然内脏痛是所有人类正常感觉系统的重要组成部分,并且是许多临床病症的突出症状,但是在该领域中没有进行太多的临床研究,并且很少有具有内脏痛管理专业知识的临床科学家。相反,内脏疼痛通常由一系列专家治疗,他们采取完全不同的方法来治疗这种类型的疼痛。因此,内脏疼痛的管理往往不令人满意。在这篇综述中,我们认为内脏痛作为一种独立的疼痛形式,并从临床角度研究其独特的感觉特性。我们描述了最近的研究结果,这些研究结果可能会改变我们对内脏疼痛的看法,更重要的是,可能有助于开发新的治疗方法。
Visceral pain is the most common form of pain produced by disease and one of the most frequent reasons why patients seek medical attention. Yet much of what we know about the mechanisms ef pain derives from experimental studies of somatic not visceral nociception. The conventional view is that visceral pain is simply a variant of somatic pain, a view based on the belief that a single neurological mechanism is responsible for all pain. However, the more we learn about the mechanisms of somatic and visceral pain, the more we realise that although these two processes have much in common, they also have important differences. Although visceral pain Is an important part of the normal sensory repertoire of all human beings and a prominent symptom of many clinical conditions, not much clinical research has been done in tills field and there are few clinical scientists with expertise In the management of visceral pain. Instead, visceral pain is usually treated by a range of specialists who take quite different approaches to the management of this type of pain. Thus, the management of visceral pain is frequently unsatisfactory. In this review, we consider visceral pain as a separate form of pain and examine its distinct sensory properties from a clinical perspective. We describe recent research findings that may change the way we think about visceral pain and, more importantly, may help develop new procedures for its management.