ESTIMATING THYROID MASSES FOR CHILDREN, INFANTS, AND FETUSES IN UKRAINE EXPOSED TO 131I FROM THE CHERNOBYL ACCIDENT

ESTIMATING THYROID MASSES FOR CHILDREN, INFANTS, AND FETUSES IN UKRAINE EXPOSED TO 131I FROM THE CHERNOBYL ACCIDENT
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DOI:
10.1097/hp.0b013e31826e188e
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发表时间:
2013-01-01
期刊:
影响因子:
2.2
通讯作者:
Tronko, M.
Tronko, M.
中科院分区:
医学4区
文献类型:
--
作者:
Likhtarov, I.;Kovgan, L.;Tronko, M.

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为了改进切尔诺贝利事故后儿童和青少年甲状腺内剂量的回顾性估计,对乌克兰北方污染最严重的两个地区-基辅和日托米尔州儿童的甲状腺肿块进行了年龄和性别相关的估计。对于6-16岁的儿童,甲状腺质量是基于20世纪90年代由Sasakawa纪念健康基金会对约60,000名儿童的甲状腺体积进行的超声测量。对于0至36个月的儿童,由于文献中未发现乌克兰儿童的甲状腺质量值,因此出于本文的特定目的进行了尸检。3-5岁和17-18岁儿童的甲状腺质量值是从测量数据集内插或外推的。6-16岁儿童的结果表明,农村儿童的甲状腺质量平均略高于城市儿童(约8%)。5岁、10岁和15岁的男孩和女孩甲状腺质量的几何平均值分别估计为5.2 g、9.0 g和15.8 g,分别为5.2 g、9.4 g和16.0 g。这些数值高于辐射防护委员会建议的碘充足人口的参考值,从而反映出乌克兰北方地区碘缺乏的事实。健康物理学104(1):78-86; 2013
For the purpose of improving retrospective internal thyroid dose estimations for children and adolescents following the Chernobyl accident, age- and gender-dependent thyroid masses have been estimated for the children of Kiev and Zhytomyr oblasts, which are two of the most contaminated regions of Northern Ukraine. For children ages 6-16 y, the thyroid masses were based on the measurements by ultrasound of the thyroid volumes of about 60,000 children performed by the Sasakawa Memorial Health Foundation in the 1990s. For children aged 0 to 36 mo, because thyroid mass values for Ukrainian children were not found in the literature, autopsies were performed for the specific purpose of this paper. Thyroid mass values for children aged 3-5 and 17-18 y were either interpolated or extrapolated from the measured data sets. The results for children aged 6-16 y indicate that the thyroid masses of rural children are, on average, slightly higher (by about 8%) than the thyroid masses of urban children. The geometric means of the thyroid masses were estimated as 5.2 g, 9.0 g, and 15.8 g for boys and 5.2 g, 9.4 g, and 16.0 g for girls aged 5, 10, and 15 y, respectively. Those values are greater than the reference values that ICRP recommends for iodine-sufficient populations, thus reflecting the fact that the northern part of Ukraine is iodine-deficient. Health Phys. 104(1):78-86; 2013