A Multicenter Prospective Cohort Study on Refractive Surgery in 15 011 Eyes
A Multicenter Prospective Cohort Study on Refractive Surgery in 15 011 Eyes
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DOI：
10.1016/j.ajo.2016.12.009
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发表时间：
2017-03-01
影响因子：
4.2
通讯作者：
Bissen-Miyajima, Hiroko
中科院分区：
文献类型：
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作者：
Kamiya, Kazutaka;Igarashi, Akihito;Bissen-Miyajima, Hiroko
目得：设计：前瞻性、多中心队列研究。方法：本前瞻性研究包括在42家主要机构接受激光原位角膜磨镶术（LASIK）、表面消融术、屈光性角膜磨镶术（ReLEx）或有晶状体眼人工透镜（IOL）植入术的7622例患者的15011只眼。我们在术前、术后1周、1个月和3个月确定了这些手术的安全性、有效性、可预测性、稳定性和不良事件。LASIK、表面消融、ReLEx、后房有晶状体眼IOL或虹膜支撑有晶状体眼IOL植入后3个月的平均logMAR矫正远视力为-0.18 +/- 0.07，-0.16 +/- 0.08，分别为-0.17 +/- 0.09、-0.21 +/- 0.08和-0.10 +/- 0.12; logMAR裸眼远视力的相应值分别为-0.15 +/-0.11，-0.12 +/-0.12，-0.12 +/-0.13，-0.15 +/-0.12，和0.01 +/-0.21。在LASIK、表面消融、ReLEx、后房型有晶状体眼IOL和虹膜支撑型有晶状体眼IOL植入后，尝试矫正的1.0屈光度（D）内的百分比分别为96%、93%、97%、99%和84%。从1周至3个月的屈光变化分别为-0.08 +/- 0.07、0.21 +/- 0.63、-0.04 +/- 0.41、0.01 +/- 0.31和0.01 +/- 0.46 D。没有视力威胁并发症发生在observationperiod.CONCLUSIONS：虽然更长时间的后续行动仍然是必要的，目前使用的屈光手术程序有良好的安全性和有效性的结果，产生可预测的和稳定的结果。当代LASIK、表面消融、ReLEx和有晶状体眼IOL植入术似乎是治疗屈光不正的可行选择。(C)2016 Elsevier Inc. All rights reserved.
PURPOSE: To assess the clinical outcomes of currently used refractive surgery procedures performed in 2015.DESIGN: Prospective, multicenter cohort study.METHODS: This prospective study included 15 011 eyes of 7622 consecutive patients who underwent laser in situ keratomileusis (LASIK), surface ablation, refractive lenticule extraction (ReLEx), or phakic intraocular lens (IOL) implantation at 42 major institutions. We determined the safety, efficacy, predictability, stability, and adverse events of these surgeries preoperatively and at 1 week and 1 and 3 months postoperatively.RESULTS: Mean logMAR corrected distance visual acuity 3 months after LASIK, surface ablation, ReLEx, posterior chamber phakic IOL, or iris-supported phakic IOL implantation was -0.18 +/- 0.07, -0.16 +/- 0.08, -0.17 +/- 0.09, -0.21 +/- 0.08, and -0.10 +/- 0.12, respectively; the corresponding values for logMAR uncorrected distance visual acuity were -0.15 +/- 0.11, -0.12 +/- 0.12, -0.12 +/- 0.13, -0.15 +/- 0.12, and 0.01 +/- 0.21, respectively. The percentages within 1.0 diopter (D) of the attempted correction were 96%, 93%, 97%, 99%, and 84% after LASIK, surface ablation, ReLEx, posterior chamber phakic IOL, and iris-supported phakic IOL implantation, respectively. Refractive change from 1 week to 3 months was -0.08 +/- 0.07, 0.21 +/- 0.63, -0.04 +/- 0.41, 0.01 +/- 0.31, and 0.01 +/- 0.46 D, respectively. No vision-threatening complications occurred during the observation period.CONCLUSIONS: Although more prolonged follow-up is still necessary, currently used refractive surgery procedures have good safety and efficacy outcomes, yielding predictable and stable results. Contemporary LASIK, surface ablation, ReLEx, and phakic IOL implantation appear to be feasible options for the treatment of refractive errors. (C) 2016 Elsevier Inc. All rights reserved.