Metabolic rate in sedentary adults, following different exercise training interventions: The FIT-AGEING randomized controlled trial
Metabolic rate in sedentary adults, following different exercise training interventions: The FIT-AGEING randomized controlled trial
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DOI：
10.1016/j.clnu.2020.02.001
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发表时间：
2020-11-01
影响因子：
6.3
通讯作者：
Castillo, Manuel J.
中科院分区：
文献类型：
--
作者：
Amaro-Gahete, Francisco J.;De-la-O, Alejandro;Castillo, Manuel J.
背景与目的：本研究比较了不同运动训练方案对久坐不动的中年人基础代谢率(BMR)和运动中脂肪氧化(MFO)的影响。方法：这项为期12周的随机对照试验的研究对象为71名中年人(年龄53.5+/-4.9岁，女性占52%)。受试者被随机分配到以下组：(1)不运动，(2)根据国际体力活动建议进行同步训练(PAR组)，(3)高强度间歇训练(HILT组)，(4)高强度间歇训练+全身肌电刺激(HILT+EMS组)。结果：HILT+EMS组干预前后BFOX显著高于对照组(均P=0.043.0 5)，PAR、HART与对照组比较差异无统计学意义(P均=0.1)。与非运动对照组相比，HART和HILT+EMS组干预后MFO显著增加(P<；0.05)；PAR组与对照组相比差异无统计学意义(均P>；=0.05)。结论：12周大强度间歇训练加全身肌电刺激可增加中年久坐成年人的BFox和MFO。这些发现具有重要的临床意义；精心设计的高强度间歇训练计划加上全身电刺激，可能有助于对抗以久坐不动的中年成年人为特征的慢性代谢性疾病的出现，尽管有必要确定这些影响会持续多久。(C)2020爱思唯尔有限公司和欧洲临床营养和代谢学会。版权所有。
Background & aims: This study compares the influence of different exercise training programs on basal metabolic rate (BMR) and fat oxidation, in basal conditions (BFox) and during exercise (MFO), in sedentary, middle-aged adults.Methods: The study subjects of this 12 week-long, randomised controlled trial, were 71 middle-aged adults (age 53.5 +/- 4.9 years; 52% women). Subjects were randomly assigned to one of the following groups: (1) no exercise, (2) concurrent training based on international physical activity recommendations (PAR group), (3) high intensity interval training (HILT group), and (4) high intensity interval training plus whole-body electromyostimulation (HILT + EMS group). Subject BMR, BFox and MFO were determined by indirect calorimetry before and after the intervention.Results: The HILT + EMS subjects showed significant increases in BFox following the intervention compared with the control group (all P = 0.043); no such differences were seen in the PAR and HILT compared with the control group (all P >= 0.1). A significant increase in post-intervention MFO was noted for the HILT and HILT + EMS group compared to the non-exercise control group (P < 0.05); no such difference was seen in the PAR group compared to the control group (all P >= 0.05).Conclusions: Twelve weeks of high intensity interval training plus whole-body electromyostimulation may increase the BFox and MFO of middle-aged sedentary adults. These findings have important clinical implications; a well-designed high-intensity interval training program plus whole-body electro-myostimulation might be followed to help combat the appearance of chronic metabolic diseases characterized by metabolic inflexibility in middle-aged sedentary adults, though it will be necessary to determine how long the effects last. (C) 2020 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.