Physical activity and obesity: what we know and what we need to know

Physical activity and obesity: what we know and what we need to know
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DOI:
10.1111/obr.12460
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发表时间:
2016-12-01
期刊:
影响因子:
8.9
通讯作者:
Binks, M.
Binks, M.
中科院分区:
医学1区
文献类型:
--
作者:
Chin, S. -H.;Kahathuduwa, C. N.;Binks, M.

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通过减少卡路里消耗和增加体力活动来创造负能量平衡是治疗肥胖的常用策略。大量的综述和原创研究论文都考虑了体力活动在减肥和维护中的作用。然而,他们的结论有时是相互矛盾的。在这篇综述中,我们对系统性综述和荟萃分析的结果进行了批判性的评估,并用最近发表的高质量临床试验补充了他们的结论。我们已经剔除了那些在方法上有缺陷的研究,试图减少文献中的歧义。我们进一步寻求,通过对这些出版物的选择性审查,分离不同类型运动的影响,独立于饮食干预,进一步阐明它们的独立贡献。因此,我们的综述描述了(I)将卡路里限制与体力活动干预相结合,(Ii)没有卡路里限制的体力活动干预,以及(Iii)体力活动在维持体重减轻中的作用。通过对文献的批判性研究,我们得出了一些结论,以解决有关体力活动在肥胖治疗中的作用的某些含糊之处,这将为临床实践提供参考。我们还发现了几个长期存在的知识空白,这些空白将为未来的研究提供信息。
Creating a negative energy balance by decreasing caloric consumption and increasing physical activity is a common strategy used to treat obesity. A large number of review and original research papers have considered the role of physical activity in weight loss and maintenance. However, their conclusions are at times conflicting. In this review, we have critically evaluated the findings of systematic reviews and meta-analyses and supplemented their conclusions with recently published, high-quality clinical trials. We have eliminated studies that were methodologically flawed in an attempt to reduce the ambiguity in the literature. We further sought, through selective review of these publications, to isolate the effects of various types of exercise, independent of dietary interventions, to further clarify their independent contributions. Thus, our review describes (i) combined calorie restriction with physical activity interventions, (ii) physical activity interventions without calorie restriction and (iii) the role of physical activity on maintenance of weight loss. Through this critical examination of the literature, we have provided conclusions to address certain ambiguities regarding the role of physical activity in obesity treatment that will inform clinical practice. We have also identified several long-standing gaps in knowledge that will inform future research.