Dimensions of Oppositional Defiant Disorder as Predictors of Depression and Conduct Disorder in Preadolescent Girls

Dimensions of Oppositional Defiant Disorder as Predictors of Depression and Conduct Disorder in Preadolescent Girls
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DOI:
10.1016/j.jaac.2010.01.016
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发表时间:
2010-05-01
影响因子:
13.3
通讯作者:
Loeber, Rolf
Loeber, Rolf
中科院分区:
医学1区
文献类型:
--
作者:
Burke, Jeffrey D.;Hipwell, Alison E.;Loeber, Rolf

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目的:探讨对立违抗障碍(ODD)而非行为障碍(CD)是否可以解释行为障碍和抑郁症之间的共病;测试是否可以在 ODD 的症状中辨别出不同的情感和行为维度;并确定 ODD 症状的情感维度是否可以明确预测以后的抑郁症。方法:在 2,451 名 5 至 8 岁女孩的社区样本中检查 ODD 的维度及其对后期 CD 和抑郁症的预测,并在 5 年期间每年进行随访,使用家长、儿童和教师问卷对精神病理学症状的严重程度进行评级。结果:在 ODD 症状中发现了负面情感、对抗行为和对抗行为的维度。负面情绪预示着后来的抑郁症。总体而言,对立和对抗行为可预测 CD,而对于白人女孩来说,负面情绪也可预测后期 CD。在控制合并症的情况下,CD 并不能预测后来的抑郁症。结论:ODD 在精神病理学的早期发展中起着关键作用。它是内化和外化精神病理学之间共病的核心,这可能是由 ODD 内的负面情感症状的一个维度引起的。这个维度与后来的 CD 的关系似乎因种族而异。 J. Am.阿卡德。儿童青少年。精神病学,2010;49(5):484-492。
Objective: To examine whether oppositional defiant disorder (ODD) rather than conduct disorder (CD) may explain the comorbidity between behavioral disorders and depression; to test whether distinct affective and behavioral dimensions can be discerned within the symptoms of ODD; and to determine whether an affective dimension of ODD symptoms is specifically predictive of later depression. Method: The dimensions of ODD and their prediction to later CD and depression were examined in a community sample of 2,451 girls between the ages of 5 and 8 years, followed up annually over a 5-year period, using parent, child, and teacher questionnaire ratings of the severity of symptoms of psychopathology. Results: Dimensions of negative affect, oppositional behavior, and antagonistic behavior were found within ODD symptoms. Negative affect predicted later depression. Oppositional and antagonistic behavior predicted CD overall, and for Caucasian girls, negative affect also predicted later CD. CD was not predictive of later depression, controlling for comorbid conditions. Conclusions: ODD plays a key role in the early development of psychopathology. It is central in the comorbidity between internalizing and externalizing psychopathology, which may be caused by a dimension of negative affective symptoms within ODD. How this dimension relates to later CD appears to vary by race. J. Am. Acad. Child Adolesc. Psychiatry, 2010;49(5) :484-492.