Postmortem assay of digoxin by radioimmunoassay.
Postmortem assay of digoxin by radioimmunoassay.
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通过放射免疫分析法对死后地高辛进行测定。
DOI：
10.1136/jcp.28.6.483
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发表时间：
1975
影响因子：
3.4
通讯作者：
J. Benstead
中科院分区：
文献类型：
--
作者：
D. Holt;J. Benstead
对先前接受地高辛维持治疗的患者的死后血液样本的分析表明，结果对于评估死亡时的数字化程度具有价值。对照病例的结果在正常治疗范围内，而怀疑与地高辛有关的六例死亡病例的“血清”地高辛水平高于治疗范围。从体内三个部位采集的血液中发现地高辛浓度存在差异，建议如果要进行死前数字化评估，应从腿部静脉采集死后血液。
Analysis of postmortem blood samples from patients previously on maintenance digoxin therapy suggests that the results are of value in assessing the degree of digitalization at the time of death. Control cases gave results within the normal therapeutic range wheras of six cases in which digoxin was suspected of being implicated in the death five had 'serum' digoxin levels above the therapeutic range. Differences in digoxin concentration were noted in blood collected from three sites in the body, and it is suggested that postmortem blood should be collected from the leg veins if assessment of antermortem digitalization is to be made.