Psychologic distress and natural menopause: A multiethnic community study
Psychologic distress and natural menopause: A multiethnic community study
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DOI：
10.2105/ajph.91.9.1435
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发表时间：
2001-09-01
影响因子：
12.7
通讯作者：
Sutton-Tyrrell, K
中科院分区：
文献类型：
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作者：
Bromberger, JT;Meyer, PM;Sutton-Tyrrell, K
目标。这项研究对参加全国性妇女健康研究的非裔美国人、白人、中国人、西班牙裔和日本妇女的社区样本中心理困扰和自然绝经之间的关系进行了研究。一组年龄在40岁到55岁之间的16065名女性提供了关于前一年月经规律、心理社会因素、健康和躯体心理症状的信息。心理困扰定义为在前2周内感到紧张、抑郁和易怒。心理困扰发生率以围绝经期早期最高(28.9%)，绝经前(20.9%)和绝经后(22%)最低。与绝经前的女性相比，围绝经期早期的女性在血管运动、睡眠症状和协变量进行调整和不调整的情况下，面临更大的痛苦风险。结论是，白人的痛苦几率明显高于其他种族/民族。心理困扰与中年月经不规律有关。重要的是要确定痛苦是否与荷尔蒙水平的变化有关，以及社会经济和文化因素可能在多大程度上影响情绪-荷尔蒙关系。
Objectives. This study examined the association between psychologic distress and natural menopause in a community sample of African American, White, Chinese, Hispanic, and Japanese women participating in a national women's health study.Methods. A cohort of 16065 women aged 40 to 55 years provided information on menstrual regularity in the previous year, psychosocial factors, health, and somatic-psychologic symptoms. Psychologic distress was defined as feeling tense, depressed, and irritable in the previous 2 weeks.Results. Rates of psychologic distress were highest in early perimenopause (28.9%) and lowest in premenopause (20.9%) and postmenopause (22%). In comparison with premenopausal women, early perimenopausal women were at a greater risk of distress, with and without adjustment for vasomotor and sleep symptoms and covariates. Odds of distress were significantly higher for Whites than for the other racial/ethnic groups,Conclusions. Psychologic distress is associated with irregular menses in midlife. It is important to determine whether distress is linked to alterations in hormone levels and to what extent a mood-hormone relationship may be influenced by socioeconomic and cultural factors.