Fascicular anatomy of human femoral nerve: Implications for neural prostheses using nerve cuff electrodes

Fascicular anatomy of human femoral nerve: Implications for neural prostheses using nerve cuff electrodes
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DOI:
10.1682/jrrd.2008.08.0097
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发表时间:
2009-01-01
影响因子:
--
通讯作者:
Triolo, Ronald J.
Triolo, Ronald J.
中科院分区:
其他
文献类型:
--
作者:
Gustafson, Kenneth J.;Pinault, Gilles C. J.;Triolo, Ronald J.

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通过神经袖带刺激恢复站立或行走的临床干预需要详细了解股神经神经解剖学。我们收集了8条股神经的所有远端分支,并描述了分支模式和直径。在4具尸体标本中,识别每个远端神经的神经束表示并向近端追踪,以创建复合股神经的神经束图。远端神经在复合股神经中始终表示为单独的神经束或不同的神经束组。复合股神经的无分支长度为1.50 +/- 0.47 cm(平均值+/-标准差)。复合股神经横截面为非圆形,长径和小径分别为10.50 +/- 1.52 mm和2.30 +/- 0.63 mm。6名受试者的体内术中测量结果与尸体结果一致。因此,通过能够选择性地刺激各个束组的单个神经假体,可以选择性地刺激由股神经支配的各个肌肉。
Clinical interventions to restore standing or stepping by using nerve Cuff stimulation require a detailed knowledge of femoral nerve neuroanatomy. We harvested eight femoral nerves with all distal branches and characterized the branching patterns and diameters. The fascicular representation of each distal nerve was identified and traced proximally to create fascicle maps of the compound femoral nerve in four cadaver specimens. Distal nerves were consistently represented as individual fascicles or distinct groups of fascicles in the Compound femoral nerve. Branch-free length of the compound femoral nerve was 1.50 +/- 0.47 cm (mean +/- standard deviation). Compound femoral nerve cross sections were noncircular with major and minor diameters of 10.50 +/- 1.52 mm and 2.30 +/- 0.63 mm, respectively. In vivo intraoperative measurements ill six Subjects were consistent with cadaver results. Selective stimulation of individual Muscles innervated by the femoral nerve may therefore be possible with a single neural prosthesis able to selectively stimulate individual groups of fascicles.