Molecular basis of the first reported clinical case of congenital combined deficiency of coagulation factors.
Molecular basis of the first reported clinical case of congenital combined deficiency of coagulation factors.
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DOI：
10.1182/blood-2017-05-782367
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发表时间：
2017-08
期刊：
影响因子：
20.3
通讯作者：
D. Jin;Brian O Ingram;D. Stafford;J. Tie
中科院分区：
文献类型：
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作者：
D. Jin;Brian O Ingram;D. Stafford;J. Tie
致编者：先天性复合维生素 K 依赖性凝血因子缺乏症 (VKCFD) 是一种罕见的常染色体隐性出血性疾病。[1][1]由于基因突变限制了 VKCFD 患者的多种维生素 K 依赖性凝血因子活性降低
To the editor: Congenital combined vitamin K–dependent coagulation factors deficiency (VKCFD) is a rare autosomal recessive bleeding disorder.[1][1] Patients with VKCFD have decreased activity in multiple vitamin K–dependent coagulation factors due to genetic mutations that limit the ability of