Sensory phenomena and obsessive-compulsive symptoms in Tourette syndrome following deep brain stimulation: Two case reports
Sensory phenomena and obsessive-compulsive symptoms in Tourette syndrome following deep brain stimulation: Two case reports
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抽动秽语综合征脑深部刺激后的感觉现象和强迫症状：两例报告
DOI：
10.1016/j.jocn.2018.06.046
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发表时间：
2018
影响因子：
2
通讯作者：
Kaido Takanobu
中科院分区：
文献类型：
--
作者：
Kano Yukiko;Matsuda Natsumi;Nonaka Maiko;Fujio Miyuki;Kono Toshiaki;Kaido Takanobu
在这里，我们评估的感觉现象（SP）和强迫症状（OCS）在两个难治性抽动秽语综合征（TS）的患者之前和之后的脑深部电刺激（DBS）针对中央-束旁复合体（CM-Pfc）-腹侧口核的双侧丘脑。基于这些临床特征的变化，我们还旨在阐明有关DBS在TS中使用的有用信息。我们使用耶鲁整体抽动严重程度量表（YGTSS）评估抽动，使用抽动先兆冲动量表（PUTS）评估先兆冲动，使用圣保罗大学感觉现象量表（USP-SPS）评估更广泛的SP，使用维度耶鲁-布朗强迫量表（DY-BOCS）评估OCS，使用整体功能评估量表（GAF）评估整体功能。我们报告了两名男性患者，他们在DBS后两年内表现出抽搐、先兆冲动和整体功能的持续改善。相比之下，患者在更广泛的SP（包括“恰到好处”的感知）和OCS方面存在差异。我们的研究结果表明，广泛的SP和OCS尺寸的系统评估是必要的，以阐明DBS在TS的有用性。
Here, we assess sensory phenomena (SP) and obsessive-compulsive symptoms (OCS) in two patients with refractory Tourette syndrome (TS) before and after deep brain stimulation (DBS) targeting the centromedian-parafascicular complex (CM-Pfc)-ventral oral nuclei of the bilateral thalami. Based on changes in these clinical features, we also aimed to elucidate useful information regarding the use of DBS in TS. We administered the Yale Global Tic Severity Scale (YGTSS) to assess tics, the Premonitory Urge for Tics Scale (PUTS) for premonitory urges, the University of São Paulo Sensory Phenomena Scale (USP-SPS) for broader SP, the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS) for OCS, and the Global Assessment of Functioning (GAF) scale for global functioning. We report on two male patients who showed consistent improvement in tics, premonitory urges, and global functioning two years after DBS. In contrast, there were differences between the patients in broader SP, including “just right” perceptions, and OCS. Our results suggest that systematic assessment of a wide range of SP and OCS dimensions is necessary to elucidate the usefulness of DBS in TS.
日本难治性抽动秽语综合征患者
DOI：
--
发表时间：
2020
期刊：
影响因子：
--
作者：
松田なつみ;野中舞子;鈴木茜音;金生由紀子;Yukiko Kano
通讯作者：
Yukiko Kano