Increasing Compliance with Mass Drug Administration Programs for Lymphatic Filariasis in India through Education and Lymphedema Management Programs
Increasing Compliance with Mass Drug Administration Programs for Lymphatic Filariasis in India through Education and Lymphedema Management Programs
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DOI：
10.1371/journal.pntd.0000728
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发表时间：
2010-06-01
影响因子：
3.8
通讯作者：
Fox, LeAnne M.
中科院分区：
文献类型：
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作者：
Cantey, Paul T.;Rout, Jonathan;Fox, LeAnne M.
背景：全世界近45%的淋巴丝虫病（LF）高危人群生活在印度。印度面临的挑战是，要达到所需的遵守其大规模药物管理（MDA）计划的水平，以中断LF传播，该计划使用乙胺嗪（DEC）或DEC加阿苯达唑。以前确定的预测和障碍，以遵守MDA计划被用来完善前MDA的教育活动。本研究的目的是评估这些改进和水肿发病率管理计划对MDA compliance.Methods的影响/主要结果：在3个领域进行随机，30个聚类调查：以社区为基础的MDA前教育加以社区为基础的水肿管理教育（Com-MDA+LM）地区，社区为基础的MDA前教育（Com-MDA）地区，和印度标准的MDA前教育（仅MDA）地区。Com-MDA+LM、Com-MDA和仅MDA地区的MDA计划依从性分别为90.2%、75.0%和52.9%（p
Background: Nearly 45% of people living at risk for lymphatic filariasis (LF) worldwide live in India. India has faced challenges obtaining the needed levels of compliance with its mass drug administration (MDA) program to interrupt LF transmission, which utilizes diethylcarbamazine (DEC) or DEC plus albendazole. Previously identified predictors of and barriers to compliance with the MDA program were used to refine a pre-MDA educational campaign. The objectives of this study were to assess the impact of these refinements and of a lymphedema morbidity management program on MDA compliance.Methods/Principal Findings: A randomized, 30-cluster survey was performed in each of 3 areas: the community-based pre-MDA education plus community-based lymphedema management education (Com-MDA+LM) area, the community-based pre-MDA education (Com-MDA) area, and the Indian standard pre-MDA education (MDA-only) area. Compliance with the MDA program was 90.2% in Com-MDA+LM, 75.0% in Com-MDA, and 52.9% in the MDA-only areas (p