Synthesis and dissipative particle dynamics simulation of cross-linkable fluorinated diblock copolymers: self-assembly aggregation behavior in different solvents.
Synthesis and dissipative particle dynamics simulation of cross-linkable fluorinated diblock copolymers: self-assembly aggregation behavior in different solvents.
复制标题
DOI：
10.1039/c1cp20186g
复制
发表时间：
2011-09
期刊：
影响因子：
--
通讯作者：
Shu-le Lin;Xiufang Wen;Zhi-qi Cai;P. Pi;D. Zheng;Jiang Cheng;Lijuan Zhang;Y. Qian;Zhuo-ru Yang-Zhuo
中科院分区：
文献类型：
--
作者：
Shu-le Lin;Xiufang Wen;Zhi-qi Cai;P. Pi;D. Zheng;Jiang Cheng;Lijuan Zhang;Y. Qian;Zhuo-ru Yang-Zhuo
发展微结构，如低分子聚集体、球形胶束和多隔室胶束，是材料科学研究的一个不断扩大的领域。通过将原子转移自由基聚合(ATRP)过程应用于可交联的含氟两嵌段共聚物，并对数据进行分析，我们能够展示出开发具有不同微结构的薄膜用于进一步生物学研究的潜力。应用耗散粒子动力学(DPD)、透射电子显微镜(TEM)和扫描电子显微镜(SEM)技术，对(甲基丙烯酸甲酯-甲基丙烯酸羟乙酯-甲基丙烯酸丁酯)-b-(全氟烷基)甲基丙烯酸乙酯(MMA-co-HEMA-co-BMA-b-FMA)可交联型含氟两嵌段共聚物(MMA-co-HEMA-co-BMA-b-FMA)的结构及其与各种微观结构聚集的关系进行了分析。对于可交联型两嵌段共聚物在溶液中的自组装，DPD模拟结果仅与聚集体形态和尺寸实验数据定性一致。这表明了一种改进的方法来创造研究用于其他研究领域的薄膜中的微结构所需的材料和方法。我们的工作考察了使用选择性溶剂是否可以很容易地扩展到制备不同形貌的聚集体，这是获得不同微结构薄膜的有效途径。DPD模拟可以作为实验的辅助工具，为实验提供其他有价值的信息。
Developing microstructures, such as low molecular aggregates, spherical micelles and multi-compartment micelles, is an expanding area of research in Materials Science. By applying an atom transfer radical polymerization (ATRP) process to cross-linkable fluorinated diblock copolymers and analyzing the data we are able to demonstrate the potential for developing films with different micro-structures for additional biological research. Applying the Dissipative Particle Dynamic (DPD) Method, Transmission Electron Microscopy (TEM) and Scanning Electron Microscopy (SEM) techniques to cross-linkable fluorinated diblock copolymers of (methyl methacrylate-co-hydroxyethyl methacrylate-co-butyl methacrylate)-b-2-(perfluoroalkyl)ethyl methacrylate (MMA-co-HEMA-co-BMA-b-FMA) we were able to analyze the structures and their relationships to the aggregation of various microstructure formations through the use of various solvents in the process. For the self-assembly of the cross-linkable diblock copolymer in solutions, the DPD simulation results are only in qualitative agreement with experimental data of aggregate morphologies and sizes. This suggests an improved approach to creating materials and methods necessary for studying microstructures in films used in other research areas. Our work examines whether using selective solvents can be easily extended to prepare aggregates with different morphologies, which is an effective shortcut to obtain films with different microstructures. DPD simulation can be considered as an adjunct to experiments and provides other valuable information for the experiment.