Membrane‐Bound IgD on Human Lymphoid Cells, with Special Reference to Immunodeficiency and Immunoproliferative Diseases
Membrane‐Bound IgD on Human Lymphoid Cells, with Special Reference to Immunodeficiency and Immunoproliferative Diseases
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人淋巴细胞上的膜结合 IgD，特别涉及免疫缺陷和免疫增殖性疾病
DOI：
10.1111/j.1600-065x.1977.tb00248.x
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发表时间：
1977
影响因子：
8.7
通讯作者：
M. Seligmann
中科院分区：
文献类型：
--
作者：
J. Preud’homme;J. Brouet;M. Seligmann
在淋巴细胞表面存在能够与抗原特异性结合的受体已得到充分证实。这些受体在免疫现象中起重要作用，例如诱导免疫应答、免疫记忆和耐受性（参考文献见Loor & Roelants 1977中的综述）。尽管胸腺衍生（T）细胞上抗原受体的确切性质仍然是现代免疫学中最有争议的问题之一，但相当数量的一致实验已经确定骨髓衍生（B）淋巴细胞抗原受体是免疫球蛋白（IG）分子。表面IG的优势类（SIg）
The presence on the lymphocyte surface of receptors capable of binding specifically with antigens is well established. These receptors play a considerable role in immunologic phenomena such as induction of the immune response, immunologic memory and tolerance (for references see reviews in Loor & Roelants 1977). Although the precise nature of antigen receptors on thymus-derived (T) cells is still one of the most controversial issues in modem immunology, a fair number of concordant experiments has established that bone marrow-derived (B) lymphocyte antigen receptors are immunoglobulin (Ig) molecules. The predominant class of surface Ig (SIg)