MX2: a high-flux undulator microfocus beamline serving both the chemical and macromolecular crystallography communities at the Australian Synchrotron.
MX2: a high-flux undulator microfocus beamline serving both the chemical and macromolecular crystallography communities at the Australian Synchrotron.
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DOI：
10.1107/s1600577518003120
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发表时间：
2018-05-01
影响因子：
2.5
通讯作者：
Caradoc-Davies TT
中科院分区：
文献类型：
--
作者：
Aragão D;Aishima J;Cherukuvada H;Clarken R;Clift M;Cowieson NP;Ericsson DJ;Gee CL;Macedo S;Mudie N;Panjikar S;Price JR;Riboldi-Tunnicliffe A;Rostan R;Williamson R;Caradoc-Davies TT
介绍了澳大利亚同步加速器的微焦点高分子晶体学光束线。 MX2 是 3 GeV 澳大利亚同步加速器中基于真空波荡器的晶体学光束线。光束线将能量范围为 4.8–21 keV 的硬 X 射线传送到 22 × 12 μm FWHM (H × V) 的焦点。在 13 keV 时，样品处的通量为 3.4 × 1012 光子 s−1。光束线终端站允许通过更新的 SSRL SAM 机器人机器人处理低温样品。该光束线非常适合弱衍射难以结晶的蛋白质、病毒颗粒、蛋白质组装体和核酸以及较小的分子，例如无机催化剂和有机药物分子。光束线现已成熟，并在过去九年中享有完整的用户计划。本文介绍了光束线的现状、未来计划以及最近的一些科学亮点。
A microfocus macromolecular crystallography beamline at the Australian Synchrotron is presented. MX2 is an in-vacuum undulator-based crystallography beamline at the 3 GeV Australian Synchrotron. The beamline delivers hard X-rays in the energy range 4.8–21 keV to a focal spot of 22 × 12 µm FWHM (H × V). At 13 keV the flux at the sample is 3.4 × 1012 photons s−1. The beamline endstation allows robotic handling of cryogenic samples via an updated SSRL SAM robot. This beamline is ideal for weakly diffracting hard-to-crystallize proteins, virus particles, protein assemblies and nucleic acids as well as smaller molecules such as inorganic catalysts and organic drug molecules. The beamline is now mature and has enjoyed a full user program for the last nine years. This paper describes the beamline status, plans for its future and some recent scientific highlights.