Petrobactin, a photoreactive siderophore produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus
Petrobactin, a photoreactive siderophore produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus
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DOI：
10.1021/ja0119088
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发表时间：
2002-01-23
影响因子：
15
通讯作者：
Butler, A
中科院分区：
文献类型：
--
作者：
Barbeau, K;Zhang, GP;Butler, A
Petrobactin 是一种双儿茶酚酸盐、α-羟基酸铁载体，由石油降解海洋细菌 Marinobacter Hydrocarbonoclastus 产生。 Petrobactin 的 Fe(III) 复合形式在自然阳光下具有光反应性，由 Fe(III)-柠檬酸盐部分介导。该反应导致 Petrobactin 配体脱羧并将 Fe(III) 还原为 Fe(II)。该报告是第一个展示由铁离子-α-羟基酸基团介导的 Fe(III)-铁载体的光反应性的报告之一。 Fe(III)-铁载体复合物的光介导脱羧作用的证明提出了关于光反应性在铁载体介导的铁吸收中可能的功能作用的问题。
Petrobactin is a bis-catecholate, α-hydroxy acid siderophore produced by the oil-degrading marine bacteriumMarinobacterhydrocarbonoclasticus. The Fe(III)-complexed form of petrobactin is photoreactive in natural sunlight, mediated by the Fe(III)-citrate moiety. The reaction results in decarboxylation of the petrobactin ligand and reduction of Fe(III) to Fe(II). This report is one of the first to show the photoreactivity of Fe(III)-siderophores mediated by the ferric ion-α-hydroxy acid group. The demonstration of light-mediated decarboxylation of an Fe(III)-siderophore complex raises questions about a possible functional role for photoreactivity in siderophore-mediated iron uptake.