Late thrombosis following treatment of in‐stent restenosis with drug‐eluting stents after discontinuation of antiplatelet therapy
Late thrombosis following treatment of in‐stent restenosis with drug‐eluting stents after discontinuation of antiplatelet therapy
复制标题
停止抗血小板治疗后用药物洗脱支架治疗支架内再狭窄后的晚期血栓形成
DOI：
10.1002/ccd.20428
复制
发表时间：
2005
影响因子：
2.3
通讯作者：
M. Sketch
中科院分区：
文献类型：
--
作者：
R. E. Waters;D. Kandzari;H. Phillips;Lawrence E. Crawford;M. Sketch
药物洗脱支架在原发冠状动脉病变的经皮治疗中的使用已变得普遍，但其在再狭窄病变中不断发展的安全性和有效性特征在很大程度上尚不清楚。我们报告了3例血管造影证实的药物洗脱支架血栓形成，这些血栓形成发生在抗血小板治疗中断后的晚期（193、237和535天）和短期内。所有3例患者均发生ST段抬高型心肌梗死，1例死亡。进一步的研究是必要的，以更好地确定相关的风险和理想的持续时间的抗血小板治疗的必要性，在这个队列的患者再狭窄病变。© 2005 Wiley利斯公司
Drug‐eluting stent usage has become commonplace for the percutaneous treatment of de novo coronary lesions, but the safety and efficacy profile for their evolving usage in restenotic lesions is largely unknown. We report three cases of angiographically confirmed drug‐eluting stent thrombosis following treatment of restenotic lesions that occurred late (193, 237, and 535 days) and shortly after interruption of antiplatelet therapy. All three patients suffered ST elevation myocardial infarction, and there was one death. Further studies are necessary to better define the associated risk and ideal duration of antiplatelet therapy necessary in this cohort of patients with restenotic lesions. © 2005 Wiley‐Liss, Inc.