Catalytic B(C6F5)3•H2O-promoted defluorinative functionalization of tertiary aliphatic fluorides
Catalytic B(C6F5)3•H2O-promoted defluorinative functionalization of tertiary aliphatic fluorides
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DOI：
10.1016/j.jfluchem.2016.11.005
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发表时间：
2017-01-01
影响因子：
1.9
通讯作者：
Moran, Joseph
中科院分区：
文献类型：
--
作者：
Dryzhakov, Marian;Richmond, Edward;Moran, Joseph
描述了一种B（C 6 F 5）3中心点H 2 O催化的叔脂肪族氟化物的脱氟官能化，其在良性反应条件下进行。该方法的合成效用通过快速有效地形成具有新安装的C（sp（3））-N、-S、-C和-O键的一系列产物来举例说明。这项研究说明了广泛的反应性，否则惰性的起始材料，并提供了一种路线，有价值的和合成代表性不足的产品，以前没有访问这样的氟化前体。(C)© 2016 Elsevier B. V.版权所有。
A B(C6F5)3 center dot H2O-catalyzed defluorinative functionalization of tertiary aliphatic fluorides is described that proceeds under benign reaction conditions. The synthetic utility of the method is exemplified through the fast and efficient formation of a range of products with newly installed C(sp(3)) -N, -S, -C and -O bonds. This study illustrates the broad reactivity of otherwise inert starting materials and provides a route to valuable and synthetically underrepresented products that have not been accessed previously from such fluorinated precursors. (C) 2016 Elsevier B.V. All rights reserved.