Reducing diabetes risk in American Indian women.

Reducing diabetes risk in American Indian women.
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降低美洲印第安女性患糖尿病的风险。

DOI:
10.1016/j.amepre.2007.11.014
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发表时间:
2008
影响因子:
5.5
通讯作者:
Herman,CarlaJ
Herman,CarlaJ
中科院分区:
医学2区
文献类型:
--
作者:
Thompson,JaniceL;Allen,Peg;Helitzer,DeborahL;Qualls,Clifford;Whyte,AynN;Wolfe,VenitaK;Herman,CarlaJ

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美国印第安人患2型糖尿病的比例很高。低强度干预对年轻美国印第安妇女糖尿病风险的影响尚不清楚。随机对照试验。设置/参与者社区为基础的;参与者是200名年轻的城市美国印第安妇女,他们被随机分为干预组和对照组。纳入标准包括自我报告的身份,年龄18-40岁,未怀孕,愿意在城市地区居住2年,并且没有2型糖尿病。在基线、6、12和18个月时进行测量。数据收集于2002-2006年,并在2006- 2007年进行分析。干预五个讨论小组会议(每月一次会议,为期5个月),重点是健康饮食,体育活动,目标设定和社会支持。次要结果包括心肺功能、胰岛素敏感性、血压、血脂、体脂百分比、BMI、水果摄入量、总糖和含糖饮料、FBG和电视观看量。随着时间的推移,干预组的平均蔬菜和水果摄入量比对照组显著增加(组与访视相互作用,分别为p=0.02和p=0.002)。两组的体脂百分比都有显著增加,腰围、胰岛素敏感性、血胆固醇、低密度脂蛋白、看电视和能量、饱和脂肪、糖和含糖饮料的总摄入量都有显著减少。美国城市印第安妇女。试验登记NCT 00438126
BACKGROUNDAmerican Indians experience high rates of type 2 diabetes. The impact of low-intensity interventions on diabetes risk among young American Indian women is unknown.DESIGNRandomized controlled trial.SETTING/PARTICIPANTSCommunity-based; participants were 200 young urban American Indian women who were block-randomized on fasting blood glucose (FBG) into intervention and control groups. Inclusion criteria included self-reported identity, aged 18–40 years, not pregnant, willingness to stay in urban area for 2 years, and not having type 2 diabetes. Measures were taken at baseline, 6, 12, and 18 months. Data were gathered in 2002–2006 and analyzed in 2006–2007.INTERVENTIONFive discussion group sessions (one meeting per month for 5 months) were held focusing on healthful eating, physical activity, goal-setting, and social support.MAIN OUTCOME MEASURESPrimary outcomes included dietary fat and vegetable consumption and self-reported physical activity. Secondary outcomes included cardiorespiratory fitness, insulin sensitivity, blood pressure, lipid profiles, percent body fat, BMI, intake of fruit, total sugar and sweetened beverages, FBG, and television viewing.RESULTSMean vegetable and fruit intake increased significantly more in the intervention group than in the control group over time (group by visit interaction, p=0.02 and p=0.002, respectively). Both groups had significant increases in percent body fat and decreases in waist circumference, insulin sensitivity, blood cholesterol, LDL, television viewing, and total intakes of energy, saturated fat, sugar, and sweetened beverages.CONCLUSIONSA culturally influenced, low-intensity lifestyle intervention can improve self-reported intakes of vegetables and fruit over 18 months in young, urban American Indian women.TRIAL REGISTRATIONNCT00438126