Noninvasive brain stimulation for motor recovery after stroke: mechanisms and future views.
Noninvasive brain stimulation for motor recovery after stroke: mechanisms and future views.
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DOI：
10.1155/2012/584727
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发表时间：
2012
影响因子：
1.5
通讯作者：
Izumi S
中科院分区：
文献类型：
--
作者：
Takeuchi N;Izumi S
重复经颅磁刺激和经颅直流电刺激是无创脑刺激（NIBS）技术，可以改变人类皮层的兴奋性。考虑到中风后发生的半球间竞争，可以通过增加受影响半球的兴奋性或降低未受影响半球的兴奋性来改善运动缺陷。许多报告表明，NIBS的应用通过利用脑卒中患者的生理特性来改善其运动功能。为了持续改善运动功能，重要的是进行额外的运动训练，同时 NIBS 调节两个半球之间的神经网络并重塑受影响半球中受到干扰的网络。 NIBS 可以作为中风患者神经康复策略的辅助治疗。此外，最近的研究表明，双侧 NIBS 可以更有效地促进神经可塑性并诱导中风后的运动恢复。然而，最佳的 NIBS 模式尚未建立，临床医生应考虑 NIBS 机制来选择 NIBS 类型。在这里，我们回顾了 NIBS 治疗的基本机制和未来观点，并提出了适当的皮质重组的康复方法。
Repetitive transcranial magnetic stimulation and transcranial direct current stimulation are noninvasive brain stimulation (NIBS) techniques that can alter excitability of the human cortex. Considering the interhemispheric competition occurring after stroke, improvement in motor deficits can be achieved by increasing the excitability of the affected hemisphere or decreasing the excitability of the unaffected hemisphere. Many reports have shown that NIBS application improves motor function in stroke patients by using their physiological peculiarity. For continuous motor improvement, it is important to impart additional motor training while NIBS modulates the neural network between both hemispheres and remodels the disturbed network in the affected hemisphere. NIBS can be an adjuvant therapy for developed neurorehabilitation strategies for stroke patients. Moreover, recent studies have reported that bilateral NIBS can more effectively facilitate neural plasticity and induce motor recovery after stroke. However, the best NIBS pattern has not been established, and clinicians should select the type of NIBS by considering the NIBS mechanism. Here, we review the underlying mechanisms and future views of NIBS therapy and propose rehabilitation approaches for appropriate cortical reorganization.