DAT imaging in drug-induced and psychogenic parkinsonism
DAT imaging in drug-induced and psychogenic parkinsonism
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DOI：
10.1002/mds.10575
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发表时间：
2003-01-01
影响因子：
8.6
通讯作者：
Gallardo, M
中科院分区：
文献类型：
--
作者：
Tolosa, E;Coelho, M;Gallardo, M
帕金森综合征（PS）常发生于与黑质纹状体通路显著变性相关的疾病，如帕金森病、多系统萎缩和进行性核上性麻痹（突触前PS）。药物引起的帕金森综合征是一种常见的、诊断不足的健康问题，而心因性帕金森综合征是帕金森综合征的原因，有证据表明，帕金森综合征的发生没有黑质纹状体结构的退化。我们回顾药物性帕金森综合征和心因性帕金森综合征的临床特征和DAT成像结果。这两种情况通常给出正常的纹状体DAT成像结果;在任何一种情况下的异常结果都可以排除这两种情况，在不确定的情况下证实器质性帕金森综合征的诊断。(C)2003年，为社会运动员。
Parkinson's syndrome (PS) is frequently encountered in disorders associated with prominent degeneration of the nigrostriatal pathway as in Parkinson's disease, multisystem atrophy, and progressive supranuclear palsy (presynaptic PS). Drug-induced parkinsonism, a common, underdiagnosed health problem and psychogenic parkinsonism are causes of Parkinson's syndrome which, evidence suggests, occurs without degeneration of nigrostriatal structures. We review clinical features and results of DAT imaging in drug-induced parkinsonism and psychogenic parkinsonism. These two conditions normally give normal striatal DAT imaging results; an abnormal result in either case could exclude both conditions, corroborating a diagnosis of organic parkinsonism in uncertain cases. (C) 2003 Movement Disorder Society.