The effects of lipids on the immune response of patients with cancer.
The effects of lipids on the immune response of patients with cancer.
复制标题
脂质对癌症患者免疫反应的影响。
DOI:
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复制
发表时间:
2000
期刊:
影响因子:
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通讯作者:
F. Kalfarentzos
中科院分区:
文献类型:
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作者:
C. Gogos;A. Skoutelis;F. Kalfarentzos
The role of diet and certain nutritional factors in the etiology or promotion of various malignant diseases has widely been studied. A link between dietary fat and cancer has long been proposed through various human epidemiologic and experimental data. High fat diets are associated with a high incidence and accelerated development of certain tumors, while there is evidence that dietary w-3 fatty acids have beneficial effects in cancer growth and metastasis. The relation between the different lipid formulations and cancer appears to be mainly related to the influence of specific fatty acids on the synthesis of the immunosuppressive prostaglandin E2. Omega-3 polyunsaturated fatty acids seem to have an anti-tumor effect through their immunomodulating, anti-inflammatory action and direct inhibition of tumor cell proliferation via alteration in prostaglandin E2 production.