2'-DEOXYNUCLEOSIDE URONIC-ACIDS FROM THE ASCIDIAN APLIDIUM-(=AMAROUCIUM)-FUSCUM (DRASCHE, 1883)

2'-DEOXYNUCLEOSIDE URONIC-ACIDS FROM THE ASCIDIAN APLIDIUM-(=AMAROUCIUM)-FUSCUM (DRASCHE, 1883)
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DOI:
10.1016/0305-0491(86)90263-4
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发表时间:
1986-01-01
影响因子:
2.2
通讯作者:
PIETRA, F
PIETRA, F
中科院分区:
生物学3区
文献类型:
--
作者:
DEMATTE, N;GUERRIERO, A;PIETRA, F

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1.胸苷-5“-羧酸1和2”-脱氧尿苷-5“-羧酸2,以前只知道是合成产物,已从东比利牛斯海岸[意大利]的海鞘Aplidium(=Amaroucium)fuscum(Drasche,1883)(Aplousobranchia目,Polyclinidae科)中分离出来。2.这些是第一个从自然界中分离的2“-脱氧核苷糖醛酸,尽管某些细菌来源的酶在工业中用于将腺苷氧化为腺苷-5”-羧酸。
1. Thymidine-5''-carboxylic acid 1 and 2''-deoxyuridine-5''-carboxylic acid 2, previously only known as synthetic products, have been isolated from the ascidian Aplidium (=Amaroucium) fuscum (Drasche, 1883) (order Aplousobranchia, family Polyclindiae) of the East Pyrenean coast [Italy]. 2. These are the first 2''-deoxynucleoside uronic acids isolated from nature, though certain enzymes of bacterial origin are used in the industry to oxidize adenosine to adenosine-5''-carboxylic acid.