Factors associated with coverage of praziquantel for schistosomiasis control in the community-direct intervention (CDI) approach in Mali (West Africa).
Factors associated with coverage of praziquantel for schistosomiasis control in the community-direct intervention (CDI) approach in Mali (West Africa).
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DOI：
10.1186/2049-9957-2-11
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发表时间：
2013-06-10
影响因子：
8.1
通讯作者：
Doumbo O
中科院分区：
文献类型：
--
作者：
Dabo A;Bary B;Kouriba B;Sankaré O;Doumbo O
尽管在控制被忽视的热带病（NTD）方面取得了进展，但在世界许多地方，血吸虫和土壤传播的蠕虫感染远未得到有效管理。化疗是所有控制策略的关键要素，但在获得治疗方面面临一些困难。我们的研究旨在描述通过控制规划的社区指导干预（CDI）方法的成功或失败所涉及的因素，该方法旨在以可负担和可持续的成本在流行地区实现持续的高覆盖率。2007年12月至2008年10月，在马里disamma区的10个村庄实施了CDI方法。在纳入时，研究样本的每个儿童部分都接受了采访并提交了体检。本研究的重点是：数据收集、符合条件人群的治疗、治疗覆盖率的评价、社区药品经销商（cdd）的绩效以及人群的参与和认知。共有8022名符合条件的人被研究，平均覆盖率为76.7%。采用多元回归分析，确定接受吡喹酮治疗与富拉尼或摩尔人少数民族与班巴拉/索宁克人、使用中央分配模式与挨家挨户分配模式、人口与cdd数之比、缺乏监管、年龄在15岁及以上5个因素相关（p<0.05）。除此之外，研究还发现，为社区成员提供财政激励的平行社区规划（艾滋病毒、结核病）的存在阻碍了许多cdd（在大多数情况下是志愿者）参与CDI方法，因为缺乏激励。调查结果显示，社区发展模式的成功与否，除其他因素外，还取决于受访者的个人特点，以及社区因素。
Despite the progress made in the control of Neglected Tropical Diseases (NTD), schistosome and soil-transmitted helminth infections are far from being effectively managed in many parts of the world. Chemotherapy, the key element of all control strategies, is faced with some difficulties in terms of access to treatment. Our study aims to describe the factors involved in the success or failure of the community-directed intervention (CDI) approach through control programmes, which aims to achieve consistent high coverage at affordable and sustainable costs in endemic areas. The CDI approach was carried out from December 2007 to October 2008 in ten villages of the district of Diéma, Mali. At inclusion, each child part of the study’s sample was interviewed and submitted for a physical examination. The study focused on: data collection, treatment of the eligible population, evaluation of the treatment coverage, performance of community drug distributors (CDDs), and the involvement and perception of populations. A total of 8,022 eligible people were studied with a mean coverage rate of 76.7%. Using multiple regression, it was determined that receiving praziquantel as treatment was associated with five factors: belonging to the Fulani or Moorish ethnic minority versus the Bambara/Soninke, use of the central versus the house-to-house drug distribution mode, the ratio of the population to the number of CDDs, the lack of supervision and belonging to the age group of 15 years or above (p<0.05). As well as that, it was found that the presence of parallel community-based programmes (HIV, tuberculosis) that provide financial incentives for community members discouraged many CDDs (who in most cases are volunteers) to participate in the CDI approach due to a lack of incentives. The findings indicate that the success of the CDI approach depends on, amongst other things, the personal characteristics of the respondents, as well as on community factors.
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影响因子：
--
作者：
Katabarwa, NM;Mutabazi, D;Richards, FO
通讯作者：
Richards, FO
DOI：
10.1016/j.trstmh.2008.04.039
发表时间：
2008-10-01
影响因子：
2.2
作者：
Njenga, S. M.;Wamae, C. N.;Molyneux, D. H.
通讯作者：
Molyneux, D. H.
影响因子：
2.7
作者：
van der Werf, MJ;de Vlas, SJ;Engels, D
通讯作者：
Engels, D
影响因子：
0.6
作者：
Sama, MT;Homeida, M;Seketeli, A
通讯作者：
Seketeli, A
影响因子：
3.3
作者：
Campagne, G;Garba, A;Chippaux, JP
通讯作者：
Chippaux, JP