Cardiovascular magnetic resonance evaluation of left ventricular peak filling rate using steady-state free precession and phase contrast sequences.
Cardiovascular magnetic resonance evaluation of left ventricular peak filling rate using steady-state free precession and phase contrast sequences.
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DOI：
10.1186/s40064-016-2878-x
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Miyatake H
中科院分区：
文献类型：
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作者：
Komi S;Inoue Y;Hata H;Nakajima A;Miyatake H
我们研究了一种实用的测量峰值充盈率(PFR)的方法，作为左室舒张功能的指标。10名成年志愿者接受了电影磁共振成像，使用稳态自由进动(SSFP)和相位对比(PC)序列来测量PFR。在二尖瓣口处采集两组PC图像，从时间分辨率较高的图像(时间PC法)和空间分辨率较高的图像(空间PC法)确定PFR。采集复盖左心室的SSFP图像，并在充盈峰值附近绘制时间-体积曲线。在LV时间-容量曲线的一阶导数曲线上用抛物线拟合法测定PFR。PC方法估计的PFR值与SSFP方法估计的值具有很好的相关性，尽管明显低估了这些值。时间预测方法的低估程度(12%)小于空间预测方法的低估程度(28%)。PC方法的观察者内和观察者间的重复性好于SSFP方法。PC成像测量PFR具有较高的真时间分辨率，操作简便，重复性好，准确度可接受，适合于临床应用。
We investigated a practical method to measure peak filling rate (PFR) as an indicator of diastolic function of the left ventricle. Ten adult volunteers underwent cine MR imaging using steady-state free precession (SSFP) and phase contrast (PC) sequences to measure PFR. Two PC image sets were acquired at the mitral valve orifice, and PFR was determined from the set with high true temporal resolution (temporal PC method) or with high spatial resolution (spatial PC method). SSFP images covering the left ventricle were acquired, and a time–volume curve was generated around the peak filling phase. PFR was determined using parabolic curve fitting on the first-derivative curve of the LV time–volume curve. PFR values estimated by the PC methods correlated well with those estimated by the SSFP method, despite apparent underestimation. The underestimation was smaller for the temporal PC method (12 %) than for the spatial PC method (28 %). Intra- and inter-observer repeatabilities were better for the PC methods than for the SSFP method. PFR measurement by PC imaging with high true temporal resolution is convenient and offers excellent repeatability and acceptable accuracy, indicating suitability for clinical use.