beta-Endorphin: primary structure of the hormone from the ostrich pituitary gland.
beta-Endorphin: primary structure of the hormone from the ostrich pituitary gland.
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β-内啡肽：来自鸵鸟垂体的激素的主要结构。
DOI：
10.1016/0006-291x(81)91876-3
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发表时间：
1981
影响因子：
3.1
通讯作者：
Oelofsen,W
中科院分区：
文献类型：
--
作者：
Naudé,RJ;Chung,D;Li,CH;Oelofsen,W
测定了鸵鸟脑垂体β-内啡肽的氨基酸序列。它由31个具有高阿片受体结合活性的氨基酸组成。建议的序列如下：h - tir - gly - gly - phe - met - ser - ser - glu - arg - gly - arg - ala - pro - leu - val - sr - leu - phe - lys - asn - ala - ile - val - lys - ser - ala - tir - lys - lys - gly - gln - oh。与其他已知β-内啡肽的初级结构相比，第一次发现6、9、10、11、12和25位残基不同。
The amino acid sequence of β-endorphin from the ostrich pituitary has been determined. It consists of 31 amino acids with high opiate receptor-binding activity. The proposed sequence is as follows: H-Tyr-Gly-Gly-Phe-Met-Ser-Ser-Glu-Arg- Gly-Arg-Ala-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Val-Lys- Ser-Ala-Tyr-Lys-Lys-Gly-Gln-OH. When compared with the primary structures of other known β-endorphins, it is the first instance that residues in positions 6, 9, 10, 11, 12 and 25 are different.