Seroepidemiologic studies of hantavirus infection among wild rodents in California
Seroepidemiologic studies of hantavirus infection among wild rodents in California
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DOI：
10.3201/eid0302.970213
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发表时间：
1997-04-01
影响因子：
11.8
通讯作者：
Reilly, K
中科院分区：
文献类型：
--
作者：
Jay, M;Ascher, MS;Reilly, K
总共对4,626只哺乳动物进行了辛诺布雷病毒抗体血清学检测。所有非啮齿类动物抗体均为阴性。在野生啮齿动物中，抗体阳性率分别为：鼠鼠8.5%、异鼠1.4%、鼠鼠< 0.1%。1921只鹿鼠中226只（11.8%）抗体阳性，其中1975年1只阳性。抗体阳性率最高的是圣诞马甲，占35只的71.4%。克鲁兹岛，南加州海岸附近。被困在人类病例发生地附近的鹿鼠（164只中有26.8%）的抗体患病率显著高于其他地点的小鼠（优势比= 4.5；95%置信区间= 1.7,11.6）。抗体流行率随海拔升高（海拔约1200米）而增加，并与内华达山脉汉坦病毒肺综合征病例的空间聚集相关。
A total of 4,626 mammals were serologically tested for antibodies to Sin Nombre virus. All nonrodent species were antibody negative. Among wild rodents, antibody prevalence was 8.5% in murids, 1.4% in heteromyids, and < 0.1% in sciurids. Of 1,921 Peromyscus maniculatus (deer mice), 226 (11.8%) were antibody positive, including one collected in 1975. The highest antibody prevalence (71.4% of 35) was found among a. maniculatus on Santa. Cruz Island, off the southern California coast. Prevalence of antibodies among deer mice trapped near sites of human cases (26.8% of 164) was significantly higher than that of mice from other sites (odds ratio = 4.5; 95% confidence interval = 1.7, 11.6). Antibody prevalence increased with rising elevation (>1,200 meters) and correlated with a spatial cluster of hantavirus pulmonary syndrome cases in the Sierra Nevada.