Hemosiderin deposition in the pancreas.
Hemosiderin deposition in the pancreas.
复制标题
含铁血黄素沉积在胰腺中。
DOI：
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发表时间：
1985
影响因子：
4.6
通讯作者：
K. Suda
中科院分区：
文献类型：
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作者：
K. Suda
对胰腺含铁血黄素沉积进行了组织病理学研究。这项研究包括3名原发性血色病患者和25名接受输血的再生障碍性贫血患者。在3例原发性血色病患者中，含铁血黄素沉积存在于腺泡组织、胰岛、胰岛和导管上皮，但主要发生在腺泡组织中。在小叶间和小叶内也发现弥漫性和不规则的纤维化。在萎缩的外分泌胰腺中，腺泡组织呈微结节状排列。在接受输血的再生障碍性贫血患者中，含铁血黄素的分布和数量大约随着输血量的增加而增加。接受大量血液的患者发生胰腺外分泌腺腺泡组织萎缩、间质纤维化和微小结节形成。因此，胰腺外分泌微结节形成是原发性血色病患者和长期接受输血的再生障碍性贫血患者的特征性发现之一。
A histopathologic study on hemosiderin deposition in the pancreas was performed. This study included three patients with primary hemochromatosis and 25 patients with aplastic anemia who were receiving blood transfusions. In the three patients with primary hemochromatosis, hemosiderin deposition was present in the acinar tissue, interstitium, islets of Langerhans, and ductal epithelium but occurred predominantly in the acinar tissue. Fibrosis was also found in the interlobular and intralobular areas in a diffuse and irregular manner. A micronodular arrangement of the acinar tissue was present in the atrophic exocrine pancreas. In patients with aplastic anemia who were receiving blood transfusions, the distribution and the quantity of hemosiderin approximately increased in accordance with the volume of blood given. Atrophy of the acinar tissue, interstitial fibrosis, and micronodular formation in the exocrine pancreas occurred in those patients who received a large volume of blood. Therefore, micronodular formation in the exocrine pancreas was one of the characteristic findings in patients with primary hemochromatosis and in patients with aplastic anemia who had received blood transfusions over a long period.