BODY-COMPOSITION OF CHILDREN RECOVERING FROM SEVERE PROTEIN-ENERGY MALNUTRITION AT 2 RATES OF CATCH-UP GROWTH
BODY-COMPOSITION OF CHILDREN RECOVERING FROM SEVERE PROTEIN-ENERGY MALNUTRITION AT 2 RATES OF CATCH-UP GROWTH
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DOI：
10.1093/ajcn/50.6.1266
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发表时间：
1989-12-01
影响因子：
7.1
通讯作者：
BROWN, KH
中科院分区：
文献类型：
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作者：
FJELD, CR;SCHOELLER, DA;BROWN, KH
22名患有严重蛋白质-能量营养不良的儿童被随机分配到允许中度(4-6g.cntdot)的饮食治疗。Kg-1.cntdo.D-1)体重增重率(MG，n=11)或快速增重率(12-16g.Kg-1.cntdo.D-1)体重增加率(RG，n=11)，以检验RG组恢复体重不足恢复参考体成分的假设。最终的总体水量为60。+-。MG组为体重的4%，62.+-。RG组(NS)两组均达到参考体成分的3%。体重增加的组成通过来自双标记水和代谢收集数据的能量和氮平衡来测量。在恢复早期，蛋白质、脂肪和水分在体重增加中的百分比(.+-.SEM)为20.+-。1%，40.+-8%，和40.+-。MG组10%，14.+-。1%，43。+-。4%，43.+-。RG组为12%。在恢复后期，这些是13。+-。1%，42.+-7%和47.+-。MG组为14%，12.+-。1%，46。+-。4%，42.+-。RG组6%。我们的结论是，用于促进体重快速增加的营养疗法恢复了参考身体成分，并显着减少了追赶生长所需的时间。
Twenty-two children with severe protein-energy malnutrition were randomly assigned to dietary treatments that permitted either moderate (4-6 g .cntdot. kg-1 .cntdot. d-1) rates of weight gain (MG, n = 11) or rapid (12-16 g .cntdot. kg-1 .cntdot. d-1) rates of weight gain (RG, n = 11) to test the hypothesis that restoration of weight deficits by the RG group restores reference body composition. Final total body water was 60 .+-. 4% of body weight in the MG group and 62 .+-. 3% in the RG group (NS) indicating reference body composition was attained by both groups. Composition of weight gained was measured by energy and nitrogen balance from doubly labeled water and metabolic collection data. In early recovery, the percent (.+-.SEM) protein, fat, and water in weight gain was 20 .+-. 1%, 40 .+-. 8%, and 40 .+-. 10% in the MG group and 14 .+-. 1%, 43 .+-. 4%, and 43 .+-. 12% in the RG group. In late recovery these were 13 .+-. 1%, 42 .+-. 7%, and 47 .+-. 14% in the MG group and 12 .+-. 1%, 46 .+-. 4%, and 42 .+-. 6% in the RG group. We conclude that the nutritional therapy used to promote rapid weight gain restores reference body composition and significantly reduces time required for catch-up growth.