Prevalence of Alzheimer's disease, vascular dementia and dementia with Lewy bodies in a Japanese population

Prevalence of Alzheimer's disease, vascular dementia and dementia with Lewy bodies in a Japanese population
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DOI:
10.1046/j.1440-1819.2001.00779.x
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发表时间:
2001-02-01
影响因子:
11.9
通讯作者:
Yamori, Y
Yamori, Y
中科院分区:
医学2区
文献类型:
--
作者:
Yamada, T;Hattori, H;Yamori, Y

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我们研究了痴呆症的患病率在日本的一个农村城镇(Amino町),使用门到门的两阶段设计。在170名被筛查为认知障碍的人中,142人被诊断为痴呆症。所有类型痴呆的患病率(例/100名65岁以上的老年人)为3.8,阿尔茨海默病(AD)为2.1,血管性痴呆(VD)为1.0,其他类型痴呆为0.7。在其他类型的痴呆症中,有4名男性患者患有路易体痴呆症(患病率:0.1),但没有额颞叶变性患者。AD的总患病率女性较高,而VD的总患病率在两性中相同。本研究的结果与西方国家的许多研究和日本最近的一些调查结果相似,明确表明AD比VD更普遍。
We studied the prevalence of dementing disorders in a rural town of Japan (Amino-cho), using a door-to-door two-phase design. Of the 170 persons screened as having cognitive impairment, 142 cases were diagnosed as having dementia. The prevalence (cases/100 aged 65 years older) was 3.8 for all types of dementia, 2.1 for Alzheimer's disease (AD), 1.0 for vascular dementia (VD) and 0.7 for other types of dementia. Among other types of dementia, there were four male patients with dementia with Lewy bodies (prevalence: 0.1), but no patients with frontotemporal lobar degeneration. The overall prevalence was higher in women for AD, while that of VD was the same in both sexes. With results similar to many previous studies in Western countries and some recent surveys in Japan, the present sudy clearly showed that AD is more prevalent than VD.