Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery
Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery
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DOI：
10.1038/s41598-019-48112-5
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发表时间：
2019-08-12
影响因子：
4.6
通讯作者：
Oshika, Tetsuro
中科院分区：
文献类型：
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作者：
Murakami, Tomoya;Okamoto, Fumiki;Oshika, Tetsuro
本研究旨在探讨黄斑视网膜脱离（RD）术后影像不等的严重程度变化，以及影像不等与视网膜显微结构的关系。该研究包括接受RD手术的26例患者的26只眼。在术前、术后3、6和12个月测量视力。在术后3、6和12个月获得了不等像度和OCT图像。术后3个月、6个月和12个月的影像不等值（平均值+/-标准差）分别为-5.3 +/-4.2%、-4.4 +/-4.4%和-3.1 +/-3.2%。术后3 - 12个月观察到显著改善（P = 0.001）。术后12个月，14只眼出现小视症，1只眼出现巨视症，11只眼无影像不等。逐步多元回归分析显示，术后12个月的影像不等的严重程度与术后黄斑囊样水肿（CME）和视网膜前膜（ERM）的发展以及术前RD的面积显著相关。总之，尽管RD手术后1年随访期间影像不等逐渐缓解，但约一半患者存在影像不等，几乎所有患者都存在视觉缩小。影像不等与术后CME、ERM和术前RD面积相关。
This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean +/- standard deviation) at 3, 6, and 12 months postoperatively were -5.3 +/- 4.2%, -4.4 +/- 4.4%, and -3.1 +/- 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively (P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.