MULTIPLE CIRCADIAN OSCILLATORS REGULATE THE TIMING OF BEHAVIORAL AND ENDOCRINE RHYTHMS IN FEMALE GOLDEN-HAMSTERS
MULTIPLE CIRCADIAN OSCILLATORS REGULATE THE TIMING OF BEHAVIORAL AND ENDOCRINE RHYTHMS IN FEMALE GOLDEN-HAMSTERS
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DOI：
10.1126/science.4001926
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发表时间：
1985-01-01
期刊：
影响因子：
56.9
通讯作者：
TUREK, FW
中科院分区：
文献类型：
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作者：
SWANN, JM;TUREK, FW
在卵巢切除雌激素处理的仓鼠中观察到垂体促黄体生成激素（LH）释放的每日一次激增，表达了完整的运动活动昼夜节律。与此相反，2 LH-浪涌发生在一个单一的24小时内的仓鼠的活动节律已解离或分裂成2个不同的组件。这些观察结果表明，行为和内分泌昼夜节律的调节由相同的多振荡器系统，这似乎是由至少2个不同的昼夜节律振荡器。
A single daily surge in pituitary luteinizing hormone [LH] release was observed in ovariectomized-estrogen-treated hamsters expressing an intact circadian rhythm of locomotor activity. In contrast, 2 LH-surges occurred within a single 24 h period in hamsters whose activity rhythm had dissociated or split into 2 distinct components. These observations indicate that both behavioral and endocrine circadian rhythms are regulated by the same multioscillator system, which seems to be composed of at least 2 distinct circadian oscillators.