REGIONAL VARIATION IN PRECUTANEOUS PENETRATION OF 14C CORTISOL IN MAN
REGIONAL VARIATION IN PRECUTANEOUS PENETRATION OF 14C CORTISOL IN MAN
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DOI：
10.1038/jid.1967.29
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发表时间：
1967-01-01
影响因子：
6.5
通讯作者：
MAIBACH, HI
中科院分区：
文献类型：
--
作者：
FELDMANN, RJ;MAIBACH, HI
氢化可的松的吸收发生在所有测试的皮肤区域。在毛囊较大或较多的区域吸收增加。头皮和前额吸收的氢化可的松的量分别是前臂腹侧的3.5倍和6倍。在具有增厚的角质层的皮肤的某些区域（例如足部）中吸收减少。看似矛盾的是，手掌对氢化可的松是可以渗透的。
Absorption of hydrocortisone occurs through all skin regions tested. Absorption is increased in regions with large or numerous hair follicles. The scalp absorbed 3.5 times and the forehead 6 times the quantity of hydrocortisone as the ventral aspect of the forearm. Absorption is decreased in some regions of skin having thickened stratum corneum, e.g. the foot. In seeming contradiction, the palm is penetrable to hydrocortisone.