AUTOANTIBODIES OF SYSTEMIC RHEUMATIC DISEASES IN THE HEALTHY ELDERLY
AUTOANTIBODIES OF SYSTEMIC RHEUMATIC DISEASES IN THE HEALTHY ELDERLY
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DOI：
10.1159/000213183
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发表时间：
1990-03-01
期刊：
影响因子：
3.5
通讯作者：
TODESCO, S
中科院分区：
文献类型：
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作者：
RUFFATTI, A;ROSSI, L;TODESCO, S
对300例健康老年人进行抗核抗体、抗心磷脂抗体和IgM类风湿因子检测，并与100例19~44岁健康老年人和352例65岁以下系统性风湿病患者进行比较。IgM类风湿因子和抗核、抗心磷脂抗体的产生增加是老年人的特征，提示在评价老年患者自身抗体谱的临床意义时应考虑对年龄的校正。
Antinuclear antibodies, anticardiolipin antibodies and IgM rheumatoid factor were determined in 300 healthy aged subjects, comparing their prevalence to that in 100 healthy subjects aged between 19 and 44 years and 352 patients under 65 tears of age, affected by various systemic rheumatic diseases. Increased production of IgM rheumatoid factor and antinuclear and anticardiolipin antibodies was found as characteristic of aged humans, and suggested that a correction for age should be considered in evaluating the clinical significance of autoantibody profiles in elderly patients.