The influence of human skin lipids on the cercarial penetration responses of Schistosoma haematobium and Schistosoma mansoni.
The influence of human skin lipids on the cercarial penetration responses of Schistosoma haematobium and Schistosoma mansoni.
复制标题
人体皮肤脂质对埃及血吸虫和曼氏血吸虫尾蚴穿透反应的影响。
作者：
C. Shiff;S. Cmelik;H. Ley;R. Kriel
用琼脂平板观察法研究了血吸虫和曼氏血吸虫尾蚴的行为。研究发现，在琼脂中添加人体皮脂改变了尾蚴的行为，诱导它们试图穿透琼脂。尾蚴不会被纯化的皮肤类固醇或胆固醇刺激，但会对从人类前臂收集的脂肪的游离脂肪酸部分产生反应。进一步的分离表明，在尾蚴中触发反应的物质是游离脂肪酸的不饱和部分。纯游离脂肪酸也引发了
The behavior of cercariae of Schistosoma haematobium and S. mansoni was studied by observation on agar plates. It was found that the addition of human skin lipid to the agar altered the behavior of the cercariae, inducing them to attempt penetration of the agar. Cercariae were not stimulated by purified skin sterols or cholesterol but responded to the free fatty acid fractions of lipid collected from human forearms. Further separation showed the substance which triggered response in the cercariae to be the unsaturated fraction of free fatty acids. Pure free fatty acids also elicited